66 Paradise Ln, Rochester, MA 02770 • 774 849-5260
1520 Greystone Dr, Gurnee, IL 60031 • 847 223-8664
7413 Clarewood Ln, Gurnee, IL 60031 • 847 548-0935
Memphis, TN
Manlius, NY
Syracuse, NY
Selkirk, NY
Menomonee Falls, WI
Lindenhurst, IL
1520 Greystone Dr, Gurnee, IL 60031 • 847 366-5510
Work
Company:
Lgm pharma
Mar 2018
Position:
Chief executive officer
Education
Degree:
Doctorates, Doctor of Philosophy
School / High School:
Auburn University
1989 to 1993
Specialities:
Philosophy, Organic Chemistry
Skills
Pharmaceutical Industry • Product Development • Start Ups • Technology Transfer • Mergers and Acquisitions • Manufacturing • Biotechnology • Chemistry • Gmp • Life Sciences • Commercialization • Leadership • Regulatory Affairs • Drug Development • Six Sigma • Continuous Improvement • Project Management • Glp • Lifesciences • Management • Mergers • Process Design • Good Laboratory Practice • Sales • Research and Development • R • Formulation
Industries
Pharmaceuticals
Us Patents
Process For Preparing 6-O-Substituted Erythromycin Derivatives
Eric J. Stoner - Kenosha WI Matthew J. Peterson - Gurnee IL Yi-Yin Ku - Buffalo Grove IL Russell D. Cink - Grayslake IL Arthur J. Cooper - Lake Villa IL Mahendra N. Deshpande - Gurnee IL Tim Grieme - Chicago IL Anthony R. Haight - Wadsworth IL David R. Hill - Gurnee IL Margaret Chi-Ping Hsu - Vernon Hills IL Steven A. King - Gurnee IL Marvin Robert Leanna - Grayslake IL Elaine C. Lee - Mundelein IL Maureen A. McLaughlin - Evanston IL Howard E. Morton - Gurnee IL James J. Napier - Antioch IL Daniel J. Plata - Wadsworth IL Prasad S. Raje - Lindenhurst IL Michael Rasmussen - Kenosha WI David Riley - Kenosha WI Steven J. Wittenberger - Mundelein IL
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C07H 100
US Classification:
536 74, 536 72, 536 185
Abstract:
In one aspect, the invention relates to a process for preparing 6-O-substituted erythromycin derivatives comprising reacting 2â-substituted and optionally 4â-substituted 9-oxime erythromycin derivatives with an alkylating agent in the presence of a palladium catalyst and phosphine. In another aspect, the invention relates to processes for preparing 6-O-substituted erythromycin ketolides using the palladium-catalyzed alkylation reaction.
Process For The Preparation Of 5-(Substituted)-10-Methoxy-2,2,4-Trimethyl-2,5-Dihydro-1H-Chromeno[3,4-F]Quinolines And Derivatives Thereof
Yi-Yin Ku - Buffalo Grove IL Timothy A. Grieme - Chicago IL Padam N. Sharma - Gurnee IL Prasad S. Raje - Lindenhurst IL Howard E. Morton - Gurnee IL Mike A. Fitzgerald - Waukegan IL
The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.
Process For The Preparation Of 5-(Substituted)-10 Methoxy-2,2,4-Trimethyl-2,5-Dihydro-1H-Chromeno [3,4-F] Quinolines And Derivatives Thereof
Yi-Yin Ku - Buffalo Grove IL 60089 Timothy A. Grieme - Chicago IL 60640 Padam N. Sharma - Gurnee IL 60031 Prasad S. Raje - Lindenhurst IL 60046 Howard E. Morton - Gurnee IL 60031 Mike A. Fitzgerald - Waukegan IL 60085
International Classification:
A61K 3144
US Classification:
546152, 546 62, 546 73, 546 95
Abstract:
The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.
The invention relates to novel processes for preparing differentially protected lysine derivatives via a novel p-anisaldehyde Schiff base intermediate and the intermediate prepared therein.
Lgm Pharma
Chief Executive Officer
Nanotherapeutics Nov 2016 - Jul 2017
President and Chief Executive Officer
Raje Consulting Services Nov 2016 - Jul 2017
Independent Consultant
Eag Laboratories Aug 2014 - Nov 2016
Senior Vice President and Head of Life Sciences Division
Cambridge Major Laboratories, Inc. Nov 2012 - Aug 2014
Vice President Api Development and Manufacturing
Education:
Auburn University 1989 - 1993
Doctorates, Doctor of Philosophy, Philosophy, Organic Chemistry
Skills:
Pharmaceutical Industry Product Development Start Ups Technology Transfer Mergers and Acquisitions Manufacturing Biotechnology Chemistry Gmp Life Sciences Commercialization Leadership Regulatory Affairs Drug Development Six Sigma Continuous Improvement Project Management Glp Lifesciences Management Mergers Process Design Good Laboratory Practice Sales Research and Development R Formulation