Philip Gotwals - Needham MA, US Antonin DeFougerolles - Brookline MA, US Roy Lobb - Westwood MA, US Victor Kotelianski - Boston MA, US
Assignee:
Biogen Idec, Inc. - Cambridge MA
International Classification:
A61K039/395 C07K016/28
US Classification:
4241441, 4241521, 53038822
Abstract:
A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
Method For The Treatment Of Inflammatory Disorders
Philip Gotwals - Needham MA, US Antonin DeFougerolles - Brookline MA, US Roy Lobb - Westwood MA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
A61K 39/395 C07K 16/28
US Classification:
4241441, 4241521, 53038822
Abstract:
A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
Method For The Treatment Of Inflammatory Disorders
Philip Gotwals - Needham MA, US Antonin De Fougerolles - Brookline MA, US Roy Lobb - Westwood MA, US Victor Kotelianski - Boston MA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
A61K 39/395 C07K 16/28
US Classification:
4241441, 4241521, 5303882
Abstract:
A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
Method For The Treatment Of Inflammatory Disorders
Philip Gotwals - Needham MA, US Antonin de Fougerolles - Brookline MA, US Roy Lobb - Westwood MA, US Victor E. Kotelianski - Boston MA, US
Assignee:
Biogen IDEC MA Inc. - Cambridge MA
International Classification:
A61K 39/395
US Classification:
4241301, 4241411, 4241431, 4241521, 4241531
Abstract:
A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
Variant Type Ii Tgf-Beta Receptor Fusion Proteins And Methods
Fusion proteins comprising a variant form of TGF-beta Type II receptor linked to a portion of an immunoglobulin constant chain are described. Also described are methods of using the fusion proteins of the invention to treat a variety of fibroproliferative disorders.
Philip Gotwals - Needham MA, US Victor Kotelianski - Boston MA, US
International Classification:
A61K039/395
US Classification:
424/146100, 424/143100
Abstract:
Disclosed is a method of treating fibrosis in a human or animal subject. The method comprises administering to the subject an effective amount of an antibody to an integrin or fragment thereof.
Global Expression Analysis Of Extracellular Matrix-Integrin Interactions In Monocytes
Antonin deFougerolles - Brookline MA, US Philip Gotwals - Needham MA, US Cynthia Green - Madison CT, US
International Classification:
C12N015/87 A61K048/00
US Classification:
435/455000, 514/044000
Abstract:
Disclosed are methods of identifying integrin modulating agents using differential gene expression. Also disclosed are method of treating atheroscerosis and inflammatory disorders in a subject.
Philip Gotwals - Needham MA, US Victor Kotelianski - Boston MA, US
International Classification:
A61K039/395
US Classification:
424/144100, 424/141100
Abstract:
Disclosed is a method of treating fibrosis in a human or animal subject. The method comprises administering to the subject an effective amount of an antibody to an integrin or fragment thereof.
Novartis Institutes For Biomedical Research (Nibr)
Global Head, Business Development and Licensing
Novartis
Executive Director, Oncology Research
Altus Group Sep 2006 - Mar 2009
Vice President, Program Management
Biogen Sep 1994 - Sep 2006
Senior Director, Program and Alliance Management
Education:
University of California, Berkeley 1987 - 1992
Doctorates, Doctor of Philosophy, Genetics
Amherst College 1982 - 1985
Bachelors, Bachelor of Arts, Biology
Northampton High School
University of Cali