Penny J Thompson

Author:

Penny Thompson

ISBN #:

0718830393

US Patent:

6610286, Aug 26, 2003

Filed:

Dec 22, 2000

Appl. No.:

09/746359

Inventors:

Penny Thompson - Snohomish WA
Donald C. Foster - Lake Forest Park WA
Wenfeng Xu - Mukilteo WA
James D. Kelly - Mercer Island WA
Hal Blumberg - Seattle WA
Yasmin A. Chandrasekher - Mercer Island WA

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 4500

US Classification:

424 852, 424 851, 4241451, 514 12, 514886, 530350

Abstract:

A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohns disease.

US Patent:

7189394, Mar 13, 2007

Filed:

Apr 28, 2003

Appl. No.:

10/424658

Inventors:

Penny Thompson - Snohomish WA, US
Donald C. Foster - Lake Forest Park WA, US
Wenfeng Xu - Mukilteo WA, US
Hal Blumberg - Seattle WA, US
Yasmin A. Chandrasekher - Mercer Island WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 39/395
A61K 39/00

US Classification:

4241301, 4241331, 4241411, 4241421, 4241451, 514 12

Abstract:

A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease.

US Patent:

7205110, Apr 17, 2007

Filed:

Oct 7, 2003

Appl. No.:

10/680755

Inventors:

Penny J. Thompson - Snohomish WA, US
Paul O. Sheppard - Granite Falls WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods of using antagonists to Zven1 and Zven2 to treat inflammation in the intestine.

US Patent:

7291589, Nov 6, 2007

Filed:

Oct 7, 2003

Appl. No.:

10/680800

Inventors:

Penny J. Thompson - Snohomish WA, US
Katherine E. Lewis - Lake Forest Park WA, US
Richard M. Garcia - Kirkland WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 38/00

US Classification:

514 2, 514 12

Abstract:

The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.

US Patent:

7364732, Apr 29, 2008

Filed:

Jul 19, 2006

Appl. No.:

11/458666

Inventors:

Penny Thompson - Snohomish WA, US
Hal Blumberg - Seattle WA, US
Yasmin A. Chandrasekher - Mercer Island WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 39/395
A61K 39/00

US Classification:

4241301, 4241331, 4241411, 4241421, 4241451, 514 12

Abstract:

A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease.

US Patent:

7531311, May 12, 2009

Filed:

Oct 19, 2006

Appl. No.:

11/550982

Inventors:

Penny J. Thompson - Snohomish WA, US
Paul O. Sheppard - Granite Falls WA, US

Assignee:

Zymogenetics, Inc. - Seattle WA

International Classification:

C12Q 1/68
C07H 21/04

US Classification:

435 6, 536 235

Abstract:

The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods of using antagonists to Zven1 and Zven2 to treat inflammation in the intestine.

US Patent:

7592312, Sep 22, 2009

Filed:

Oct 12, 2006

Appl. No.:

11/548805

Inventors:

Penny J. Thompson - Snohomish WA, US
Katherine E. Lewis - Lake Forest Park WA, US
Richard M. Garcia - Kirkland WA, US
Robert R. West - Seattle WA, US
Paul O. Sheppard - Fall City WA, US

Assignee:

Zymogenetics, Inc. - Seattle WA

International Classification:

A61K 38/00

US Classification:

514 12, 530350

Abstract:

The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.

US Patent:

8003104, Aug 23, 2011

Filed:

Apr 30, 2009

Appl. No.:

12/433784

Inventors:

Penny Thompson - Snohomish WA, US
Hal Blumberg - Seattle WA, US
Yasmin A. Chandrasekher - Mercer Island WA, US
Julia E. Novak - Bainbridge Island WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 39/395
C07K 16/24
A61K 38/00

US Classification:

4241451, 4241411, 4241421, 4241301, 4241331, 530351, 5303891, 514 122

Abstract:

A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease.