Pejman Soroosh

US Patent:

20200016205, Jan 16, 2020

Filed:

Jun 25, 2019

Appl. No.:

16/451426

Inventors:

- Beerse, BE
Anindya Bhattacharya - San Diego CA, US
Noel Christopher Derecki - San Diego CA, US
Pejman Soroosh - San Diego CA, US

International Classification:

A61K 35/17
A61K 38/20
A61P 25/00
A61P 29/00
A61P 37/06

Abstract:

Compositions and methods of using ILC2 to reduce microglial activation or to reduce blood-brain barrier (BBB) permeability are described. Also described are methods and compositions that use an agent that increases the number of activated ILC2 to reduce microglial activation or BBB permeability.

US Patent:

20180355061, Dec 13, 2018

Filed:

Jun 4, 2018

Appl. No.:

15/997148

Inventors:

- Horsham PA, US
Suzanne Cole - Spring House PA, US
Karen Duffy - Spring House PA, US
Yanxia Guo - Spring House PA, US
Debra Gardner - Spring House PA, US
Damon Hamel - San Diego CA, US
Shannon Hitchcock - Spring House PA, US
Ann Lacombe - San Diego CA, US
Jinquan Luo - Spring House PA, US
Ravi Malaviya - Spring House PA, US
Pejman Soroosh - San Diego CA, US
Melissa Swiecki - Spring House PA, US
Deepti Wilkinson - San Diego CA, US

International Classification:

C07K 16/40
A61P 37/06
C07K 16/18
C07K 16/06
A61K 39/395

Abstract:

Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.