Paul Phillipp Jackson

Author:

Paul D. Jackson

ISBN #:

3790819573

Author:

Paul A. Jackson

ISBN #:

0517405083

Author:

Paul A. Jackson

ISBN #:

0711015120

Author:

Paul Norman Jackson

ISBN #:

0773424172

Author:

Paul R. Jackson

ISBN #:

0761952829

Author:

Paul R. Jackson

ISBN #:

0761952837

Author:

Paul R. Jackson

ISBN #:

0872270130

Author:

Paul R. Jackson

ISBN #:

0872270726

Address:

1122 Cherry Pt Rd, West River, MD 20778

Phone:

410 867-4909

VIN:

1ZEAAALB57A141961

Make:

Mitsubishi

Model:

Raider Double Cab V8 Aut

Year:

2007

US Patent:

6346536, Feb 12, 2002

Filed:

Sep 3, 1997

Appl. No.:

08/922548

Inventors:

Jia-He Li - Cockeysville MD
Paul F. Jackson - Bel Air MD
Keith M. Maclin - Baltimore MD
Jie Zhang - Ellicott City MD

Assignee:

Guilford Pharmaceuticals Inc. - Baltimore MD

International Classification:

A61K 3144

US Classification:

514286, 514288, 546 66, 546 72, 546 76, 549224, 549384, 424418, 424419, 424420

Abstract:

Poly(ADP-ribose) polymerase (âPARPâ) inhibitors and methods for treating neurodegenerative diseases, neural tissue damage related to cerebral ischemia and reperfusion injury, and cardiovascular in an animal.

US Patent:

6348464, Feb 19, 2002

Filed:

Nov 12, 1999

Appl. No.:

09/438970

Inventors:

Paul F. Jackson - Bel Air MD
Barbara S. Slusher - Kingsville MD

Assignee:

Guilford Pharmaceuticals, Inc. - Baltimore MD

International Classification:

A61K 3153

US Classification:

514241, 514422, 514423, 514385, 514388, 514396, 514401, 514402, 514255, 514256, 514260, 514272, 514588, 514595, 514597, 514249, 514252

Abstract:

The present invention relates to pharmaceutical compositions and methods of using pyrrolecarbonylimino derivatives to inhibit N-Acetylated -Linked Acidic Dipeptidase (NAALADase) enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases and cancers.

US Patent:

6372726, Apr 16, 2002

Filed:

Sep 27, 1999

Appl. No.:

09/405842

Inventors:

Barbara S. Slusher - Kingsville MD
Paul F. Jackson - Bel Air MD
Kevin L. Tays - Elkridge MD
Keith M. Maclin - Baltimore MD

Assignee:

Guilford Pharmaceuticals Inc. - Baltimore MD

International Classification:

A61K 3166

US Classification:

514 75, 562 8, 562 12, 514908

Abstract:

The present disclosure relates to dipeptidase inhibitors, and more particularly, to novel methods of using phosphonate derivatives, hydroxyphosphinyl derivatives, and phosphoramidate derivatives to inhibit N-Acetylated -Linked Acidic Dipeptidase (NAALADase) enzyme activity, and to treat prostate diseases, especially using the compounds of the present invention for the inhibition of the growth of prostate cancer cells.

US Patent:

6380211, Apr 30, 2002

Filed:

Nov 15, 2000

Appl. No.:

09/711953

Inventors:

Paul F. Jackson - Bel Air MD
Keith M. Maclin - Baltimore MD
Jie Zhang - Ellicott City MD

Assignee:

Guilford Pharmaceutical Inc. - Baltimore MD

International Classification:

A61K 3147

US Classification:

514309, 5142335, 546141, 544128

Abstract:

A compound, compositions, methods of use, and processes of making formula I: or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof, wherein: R , when present, is hydrogen or lower alkyl; R is lower alkyl, aryl, aralkyl, lower alkanoyl, or â(CH ) â(CHOH) (CH ) A, wherein n is 1-4, y is 0 or 1, m is 0-5, and A is cycloalkyl, cycloalkenyl, lower alkanoyl, aryl, aralkyl, âNH , âNHâ(lower alkyl), Y represents the atoms necessary to form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; Z is (i) âCHR CHR â where R and R are independently hydrogen, alkyl, aryl or aralkyl; (ii) âR C CR â where R and R are independently hydrogen, lower alkyl, aryl, aralkyl, chlorine, bromine or âNR R , where R and R are independently hydrogen or lower alkyl, or, R and R , taken together, form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; (iii) âR C Nâ; (iv) âCR (OH)âNR â; or (v) âC(O)âNR â.

US Patent:

6384022, May 7, 2002

Filed:

Dec 31, 1997

Appl. No.:

09/001667

Inventors:

Paul F. Jackson - Bel Air MD
Barbara S. Slusher - Kingsville MD

Assignee:

Guilford Pharmaceuticals Inc. - Baltimore MD

International Classification:

A61K 3166

US Classification:

514121, 558180

Abstract:

The present invention relates to prodrugs of NAALADase inhibitors, pharmaceutical compositions comprising the same, and methods of using the same to treat glutamate abnormalities and prostate diseases.

US Patent:

6413948, Jul 2, 2002

Filed:

Sep 2, 1999

Appl. No.:

09/388442

Inventors:

Barbara S. Slusher - Kingsville MD
Paul F. Jackson - Bel Air MD
Kevin L. Tays - Elkridge MD
Keith M. Maclin - Baltimore MD

Assignee:

Guilford Pharmaceuticals Inc. - Baltimore MD

International Classification:

A61K 3166

US Classification:

514121, 514114, 514 75, 514 89, 514138

Abstract:

The present invention relates to a method of treating a glutamate abnormality and a method of effecting a neuronal activity in an animal using a NAALADase inhibitor, and a pharmaceutical composition comprising an effective amount of a NAALADase inhibitor for treating a glutamate abnormality and effecting a neuronal activity in an animal.

US Patent:

6426415, Jul 30, 2002

Filed:

May 15, 1998

Appl. No.:

09/079508

Inventors:

Paul F. Jackson - Bel Air MD
Keith M. Maclin - Baltimore MD
Jie Zhang - Ellicott City MD

Assignee:

Guilford Pharmaceuticals Inc. - Baltimore MD

International Classification:

C07D23730

US Classification:

544237, 546137

Abstract:

A compound of formula I: or a pharmaceutically acceptable salt, prodrug, metabolite, optical isomer or stereoisomer thereof, wherein: R , when present, is hydrogen or lower alkyl; R is lower alkyl, aryl, aralkyl, lower alkanoyl, or â(CH ) â(CHOH) (CH ) A, wherein n is 1-4, y is 0 or 1, m is 0-5, and A is cycloalkyl, cycloalkenyl, lower alkanoyl, aryl, aralkyl, âNH , âNH-(lower alkyl), Y represents the atoms necessary to form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; Z is (i) âCHR CHR â where R and R are independently hydrogen, alkyl, aryl or aralkyl; (ii) âR C CR â where R and R are independently hydrogen, lower alkyl, aryl, aralkyl, chlorine, bromine or âNR R , where R and R are independently hydrogen or lower alkyl, or, R and R , taken together, form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; (iii) âR C Nâ; (iv) âCR (OH)âNR â; or (v) âC(O)âNR â.

US Patent:

6458775, Oct 1, 2002

Filed:

Jul 2, 1999

Appl. No.:

09/346711

Inventors:

Paul F. Jackson - Bel Air MD
Keith M. Maclin - Baltimore MD
Eric Wang - Baltimore MD
Barbara S. Slusher - Kingsville MD
Rena S. Lapidus - Baltimore MD
Pavel Majer - Sykesville MD

Assignee:

Guilford Pharmaceutical Inc. - Baltimore MD

International Classification:

A61K 3166

US Classification:

514 75, 514143, 514277, 514574

Abstract:

The present invention relates to N-Acetylated -Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases, pain and diabetic neuropathy.