Karl Schmidt - Wauwatosa WI, US Paul Glenn - Wellesley MA, US Steven Mersch - Germantown OH, US
International Classification:
G06M 7/00 G02F 1/01
US Classification:
250225000, 250221000
Abstract:
Methods, apparatus, and systems for providing feedback to a subject in connection with a performance of a task, such as a movement task. The movement task may involve an operation or movement of an object by the subject, such as a body part or a sporting implement. During the movement task, the object has an expected motion path that is associated with one or more target areas. Behavior control feedback may be provided to the subject based on one or more of a position of the object, a motion of the object and an orientation of the object relative to one or more target areas as the subject performs the movement task. One example of an apparatus for providing behavior control feedback includes one or more radiation sources, one or more radiation detectors, and one or more indicators, any of which may be coupled to or otherwise integrated with the object. The object is operated to perform the movement task such that radiation emitted from a source of the apparatus impinges on one or more target areas covered with one or more reflectors. A radiation detector of the apparatus detects radiation that is reflected from the target areas, and an indicator coupled to the detector provides the behavior control feedback to the subject based on the detected radiation.
Methods And Apparatus For Providing Feedback To A Subject In Connection With Performing A Task
Karl B. Schmidt - Wauwatosa WI, US Paul E. Glenn - Wellesley MA, US Steven H. Mersch - Germantown OH, US
International Classification:
G01B 11/26 H01J 40/14
US Classification:
3561521, 250221, 250225
Abstract:
Methods, apparatus, and systems for providing feedback to a subject in connection with a performance of a task, such as a movement task. The movement task may involve an operation or movement of an object by the subject, such as a body part or a sporting implement. During the movement task, the object has an expected motion path that is associated with one or more target areas. Behavior control feedback may be provided to the subject based on one or more of a position of the object, a motion of the object and an orientation of the object relative to one or more target areas as the subject performs the movement task. One example of an apparatus for providing behavior control feedback includes one or more radiation sources, one or more radiation detectors, and one or more indicators, any of which may be coupled to or otherwise integrated with the object. The object is operated to perform the movement task such that radiation emitted from a source of the apparatus impinges on one or more target areas covered with one or more reflectors. A radiation detector of the apparatus detects radiation that is is reflected from the target areas, and an indicator coupled to the detector provides the behavior control feedback to the subject based on the detected radiation.
Method And Device For Noncontacting Self-Referencing Measurement Of Surface Curvature And Profile
Measurement of curvature and profile of a reflective test surface by simultaneous measurement of slope at two closely spaced points on the test surface. A pair of parallel, nearly collimated light beams, which are slightly displaced relative to each other and of opposite linear polarization, and which intersect the test surface are reflected by the test surface, separated by a polarizing beam splitter and focused onto individual position sensitive detectors, which sense the slopes of the test surface at the points where it is intersected by the beams. The difference between the measured slopes is proportional to the local curvature. The device can be scanned along the surface to give a profile of measured curvature values, which are twice integrated to give the surface profile, although measurement at a single point without any such processing yields the test piece curvature. The device is reconfigured to test surfaces with different curvatures by virtue of one of the detectors being movable during initial alignment, and by virtue of a steering mirror and associated servo control system which maintain an essentially constant angle of incidence on the test surface.
- Los Angeles CA, US Stephen D. Klyce - Port Washington NY, US John R. Rogers - Monrovia CA, US R Stephen Mulder - Tuscon AZ, US Mark A. Kahan - Marlborough MA, US Paul E. Glenn - Wellesley MA, US
International Classification:
A61B 3/107 A61B 3/00 A61B 3/135 A61B 3/15
Abstract:
A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.
Integrated Device With External Light Source For Probing Detecting And Analyzing Molecules
- Guilford CT, US Ali Kabiri - Guilford CT, US Jason W. Sickler - Arlington MA, US Jeremy Lackey - Foster City CA, US Gerard Schmid - Guilford CT, US Benjamin Cipriany - Branford CT, US Jack Jewell - Boulder CO, US Lawrence C. West - San Jose CA, US Michael Ferrigno - Farmington CT, US Paul E. Glenn - Wellesley MA, US Anthony Bellofiore - Glastonbury CT, US
Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An integrated device includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits radiation; at least one element for directing the emission radiation in a particular direction; and a light path along which the emission radiation travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the integrated device. Each sensor may detect emission radiation from a sample in a respective sample well. The instrument includes an excitation light source for exciting the sample in each sample well.
Photonic Structures And Integrated Device For Detecting And Analyzing Molecules
- Guilford CT, US Ali Kabiri - Guilford CT, US Gerard Schmid - Guilford CT, US Keith G. Fife - Palo Alto CA, US James Beach - Austin TX, US Jason W. Sickler - Arlington MA, US Lawrence C. West - San Jose CA, US Paul E. Glenn - Wellesley MA, US Kyle Preston - Guilford CT, US Farshid Ghasemi - Guilford CT, US Benjamin Cipriany - Branford CT, US Jeremy Lackey - Foster City CA, US
System and methods for analyzing single molecules and performing nucleic acid sequencing. An integrated device may include multiple pixels with sample wells configured to receive a sample, which when excited, emits radiation. The integrated device includes a surface having a trench region recessed from a portion of the surface and an array of sample wells, disposed in the trench region. The integrated device also includes a waveguide configured to couple excitation energy to at least one sample well in the array and positioned at a first distance from a surface of the trench region and at a second distance from the surface in a region separate from the trench region. The first distance is smaller than the second distance. The system also includes an instrument that interfaces with the integrated device. The instrument may include an excitation energy source for providing excitation energy to the integrated device by coupling to an excitation energy coupling region of the integrated device.
- Guilford CT, US Jason W. Sickler - Arlington MA, US Lawrence C. West - San Jose CA, US Faisal R. Ahmad - Guilford CT, US Paul E. Glenn - Wellesley MA, US Jack Jewell - Boulder CO, US John Glenn - Carlisle MA, US Jose Camara - Saratoga CA, US Jeremy Christopher Jordan - Cromwell CT, US Todd Rearick - Cheshire CT, US Farshid Ghasemi - Guilford CT, US Jonathan C. Schultz - Guilford CT, US Keith G. Fife - Palo Alto CA, US
Apparatus and methods for producing ultrashort optical pulses are described. A high-power, solid-state, passively mode-locked laser can be manufactured in a compact module that can be incorporated into a portable instrument for biological or chemical analyses. The pulsed laser may produce sub-100-ps optical pulses at a repetition rate commensurate with electronic data-acquisition rates. The optical pulses may excite samples in reaction chambers of the instrument, and be used to generate a reference clock for operating signal-acquisition and signal-processing electronics of the instrument.
Optical System And Assay Chip For Probing, Detecting And Analyzing Molecules
- Guilford CT, US Ali Kabiri - Guilford CT, US Jason W. Sickler - Arlington MA, US Brett J. Gyarfas - Aptos CA, US Jeremy Lackey - Foster City CA, US Gerard Schmid - Guilford CT, US Jack Jewell - Boulder CO, US Lawrence C. West - San Jose CA, US Michael Ferrigno - Farmington CT, US Paul E. Glenn - Wellesley MA, US Adam Ezra Cohen - Cambridge MA, US Anthony Bellofiore - Glastonbury CT, US
Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An apparatus can include an assay chip that includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits emission energy; at least one element for directing the emission energy in a particular direction; and a light path along which the emission energy travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the assay chip. The instrument includes an excitation light source for exciting the sample in each sample well; a plurality of sensors corresponding the sample wells. Each sensor may detect emission energy from a sample in a respective sample well. The instrument includes at least one optical element that directs the emission energy from each sample well towards a respective sensor of the plurality of sensors.