Nima Aflatooni

US Patent:

20060051252, Mar 9, 2006

Filed:

Sep 9, 2005

Appl. No.:

11/223095

Inventors:

Bob Yuan - Belmont CA, US
Nima Aflatooni - Berkeley CA, US

International Classification:

B32B 27/12

US Classification:

422102000

Abstract:

A handheld and portable extraction device is directed to a microfluidic-based system to be used in the field to extract and purify an analyte, preferably a nucleic acid, from a fluid-based sample. Preferably, the fluid-based sample is water-based. The fluid-based sample can also be a biological fluid sample. The handheld and portable extraction device includes a syringe-like device coupled to a purification chip. The purification chip is preferably included within a chip block which is removable from the remaining portion of the handheld and portable extraction device. The analyte collected within the purification chip can be later removed and collected for analysis.

US Patent:

20060134687, Jun 22, 2006

Filed:

Feb 9, 2006

Appl. No.:

11/351843

Inventors:

Bob Yuan - Belmont CA, US
Nima Aflatooni - Berkeley CA, US

International Classification:

C12Q 1/68
C12N 1/08
C12M 1/34

US Classification:

435006000, 435270000, 435287200

Abstract:

A differential extraction system is directed to a microfluidic-based integrated cartridge to automate differential extraction of specific cell types within a mixed sample. The integrated cartridge includes a sonication module for selective cell lysis, separating means to eliminate centrifugation, high surface area pillar chip modules to purify DNA from a cell lysate, and microfluidic circuitry to integrate the steps in an automated platform.