Techniques for determining values for a metric of microscale interactions include determining a mesoscale metric for a plurality of mesoscale interaction types, wherein a value of the mesoscale metric for each mesoscale interaction type is based on a corresponding function of values of the microscale metric for the plurality of the microscale interaction types. A plurality of observations that indicate the values of the mesoscale metric are determined for the plurality of mesoscale interaction types. Values of the microscale metric are determined for the plurality of microscale interaction types based on the plurality of observations and the corresponding functions and compressed sensing.
Protein Structures From Amino-Acid Sequences Using Neural Networks
- Cambridge MA, US Mohammed AlQuraishi - Cambridge MA, US
International Classification:
G16B 15/00 G16B 45/00
Abstract:
The present disclosure provides for systems and methods for generating and displaying a three dimensional map of a protein sequence. An exemplary method can provide for using deep learning models to predict protein folding and model protein folding using three dimensional representations. The method more effectively exploits the potential of deep learning approaches. The method approach overall involves three stages—computation, geometry, and assessment.
Compressed Sensing For Simultaneous Measurement Of Multiple Different Biological Molecule Types In A Sample
- Palo Alto CA, US Mohammed N. AlQuraishi - Cambridge MA, US Solomon Itani - Vallejo CA, US Garry P. Nolan - Menlo Park CA, US Sean C. Bendall - San Mateo CA, US Tyler J. Burns - Stanford CA, US
International Classification:
G06F 19/18
Abstract:
A method and apparatus for simultaneously determining multiple different biological molecule types in a sample include labeling each different biological molecule type in a biological sample with a unique combination of a plurality of labels. Each different biological molecule type is selected from a population of M different biological molecules types. The plurality of labels is selected from a population of L different labels; and, M is greater than L. Measurements are obtained of relative abundances of the L different labels in the sample. Relative abundance of up to M different biological molecule types in the sample are determined based on the measurements and a method of compressed sensing.
Compressed Sensing For Simultaneous Measurement Of Multiple Different Biological Molecule Types In A Sample
Karen Sachs - Palo Alto CA, US Mohammed N. AlQuraishi - Stanford CA, US Solomon Itani - Vallejo CA, US Garry P. Nolan - Menlo Park CA, US Sean C. Bendall - San Mateo CA, US Tyler J. Burns - Stanford CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G06F 19/18
US Classification:
506 9, 506 12, 506 39, 506 18
Abstract:
A method and apparatus for simultaneously determining multiple different biological molecule types in a sample include labeling each different biological molecule type in a biological sample with a unique combination of a plurality of labels. Each different biological molecule type is selected from a population of M different biological molecules types. The plurality of labels is selected from a population of L different labels; and, M is greater than L. Measurements are obtained of relative abundances of the L different labels in the sample. Relative abundance of up to M different biological molecule types in the sample are determined based on the measurements and a method of compressed sensing.
Columbia University In the City of New York
Assistant Professor of Systems Biology
Harvard Medical School
Systems Biology Fellow
Wolfram Oct 2003 - Jun 2005
Research Associate
Education:
Stanford University School of Medicine 2005 - 2011
Doctorates, Doctor of Philosophy, Genetics, Philosophy
Stanford University 2010 - 2010
Masters, Statistics
Santa Clara University 1998 - 2003
Bachelors, Computer Engineering
Santa Clara University 2001 - 2003
Bachelors, Biology
Skills:
Computational Biology Molecular Biology Bioinformatics Machine Learning Genetics Systems Biology Artificial Intelligence Statistics Data Mining Genomics Mathematical Modeling Biochemistry Biophysics Data Science Matlab Mathematica R Life Sciences Structural Bioinformatics Scientific Computing
Googleplus
Mohammed Alquraishi
Lived:
Cambridge, MA Bay Area, California
Work:
Harvard Medical School - Systems Biology Fellow (2012)
Education:
Stanford University - Genetics
About:
I am a Systems Biology Fellow at Harvard Medical School studying the molecular recognition problem.
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