Mina Buenafe - Miami Beach FL, US Michael Brucato - Miami Shores FL, US Kai Zhang - Miami FL, US
International Classification:
A61L009/04 A61K031/573 A61K031/375
US Classification:
424/045000, 514/171000, 514/474000
Abstract:
The present invention thus provides chemically and physically stable formulations of glucocorticosteroids (such as, for example, budesonide) obtained by formulating the glucocorticosteroid with a cosolvent (such as ethanol), a propellant (such as HFA-134a, HFA-227ea, or both), and a radical quencher (such as ascorbyl palmitate), where the glucocorticosteroid remains chemically and physically stable under standard conditions