The present invention provides tagged acyl phosphate probes (“TAPPs”), and methods of their preparation and use. The subject methods and compositions can provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixture, preferably nucleotide binding proteins using nucleotide binding protein-directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.
6-Cycloamino-2-Quinolinone Derivatives As Androgen Receptor Modulator Compounds
Lin Zhi - San Diego CA, US Esther Martinborough - San Diego CA, US Yixing Shen - Encinitas CA, US Thomas Lot Stevens Lau - San Diego CA, US Min Wu - San Diego CA, US Yun Oliver Long - San Diego CA, US
Assignee:
Ligand Pharmaceuticals Incorporated - San Diego CA
International Classification:
C07D 215/38 A61K 31/02
US Classification:
514312, 514313, 514314, 546159, 546161
Abstract:
The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR. Also provided are methods of making such compounds and pharmaceutical compositions.
David Campbell - San Diego CA, US David Winn - San Diego CA, US Juan Betancort - San Diego CA, US Kevin Shreder - San Diego CA, US Yi Hu - San Diego CA, US Bei Li - San Diego CA, US Melissa Wong - San Diego CA, US Lifu Ma - Melville NY, US William Ripka - San Diego CA, US Min Wu - Sunnyvale CA, US
International Classification:
A61K 31/69 C07F 5/02
US Classification:
514064000, 548110000, 548405000
Abstract:
Dipeptidyl peptidase IV (DPP-IV)-inhibiting compounds are provided that have formula I: wherein n is 1 to 3; X is CH; S; O; CFor C(CH); Z is H; halogen; hydroxyl; (C)alkoxy; (C)alkyl; (C)cycloalkyl; phenyl; or heteroaryl; where the phenyl and heteroaryl groups are optionally mono- or independently plurisubstituted with R; optionally, X together with an adjacent ring carbon and Z form a fused cyclopropyl; and optionally, one of the bonds in the ring containing X is a double bond; and CRR, R, R, R, Rand Rare as described herein.
Reconfigurable Wireless Modem Sub-Circuits To Implement Multiple Air Interface Standards
Arunava Chaudhuri - San Diego CA, US Iwen Yao - San Diego CA, US Jeremy H. Lin - San Diego CA, US Ali Rostampisheh - San Diego CA, US Raghu Challa - San Diego CA, US Hamanth Sampath - San Diego CA, US Min Wu - San Diego CA, US Joseph Zanotelli - San Diego CA, US Mrinal M. Nath - San Diego CA, US
Assignee:
QUALCOMM Incorporated - San Diego CA
International Classification:
H04W 88/16 G06F 9/46
US Classification:
370329, 718100
Abstract:
A flexible and reconfigurable digital system (for example, a wireless modem) includes a set of sub-circuits. Each sub-circuit includes a task manager and an amount of configurable hardware circuitry for performing a type of operation on a data stream. The task manager of a sub-circuit can configure and control the configurable hardware of the sub-circuit. A central processor configures and orchestrates operation of the sub-circuits by maintaining a set of task lists in a tightly coupled memory. Each task list includes task instructions for a corresponding sub-circuit. The task manager of a sub-circuit reads task instructions from its task list and controls its associated hardware circuitry as directed by the instructions. A timestamp task instruction and a push task instruction and the task list architecture allow modem sub-circuits to be easily reconfigured to operate in accordance with either a first air interface standard or a second air interface standard.
Reuse Engine With Task List For Fast Fourier Transform And Method Of Using The Same
Arunava Chaudhuri - San Diego CA, US Hemanth Sampath - San Diego CA, US Iwen Yao - San Diego CA, US Jeremy H. Lin - San Diego CA, US Raghu N. Challa - San Diego CA, US Min Wu - San Diego CA, US
Assignee:
QUALCOMM Incorporated - San Diego CA
International Classification:
G06F 17/14
US Classification:
708404
Abstract:
An improved processing engine for performing Fourier transforms includes an instruction processor configured to process sequential instruction software commands and a Fourier transform engine coupled to the instruction processor. The Fourier transform engine is configured to perform Fourier transforms on a serial stream of data. The Fourier transform engine is configured to receive configuration information and operational data from the instruction processor via a set of software tasks.
System And Method For Confidentiality-Preserving Rank-Ordered Search
Ashwin SWAMINATHAN - San Diego CA, US Yinian Mao - San Diego CA, US Hongmei Gou - Germantown MD, US Avinash L. Varna - Greenbelt MD, US Shan He - Plainsboro NJ, US Min Wu - Clarksville MD, US Douglas W. Oard - College Park MD, US
International Classification:
G06F 17/30 H04L 9/00
US Classification:
713189, 707728, 707705, 707E17014, 707E17017
Abstract:
A confidentiality preserving system and method for performing a rank-ordered search and retrieval of contents of a data collection. The system includes at least one computer system including a search and retrieval algorithm using term frequency and/or similar features for rank-ordering selective contents of the data collection, and enabling secure retrieval of the selective contents based on the rank-order. The search and retrieval algorithm includes a baseline algorithm, a partially server oriented algorithm, and/or a fully server oriented algorithm. The partially and/or fully server oriented algorithms use homomorphic and/or order preserving encryption for enabling search capability from a user other than an owner of the contents of the data collection. The confidentiality preserving method includes using term frequency for rank-ordering selective contents of the data collection, and retrieving the selective contents based on the rank-order.
Raheel Khan - Tustin CA, US Min Wu - San Diego CA, US
Assignee:
QUALCOMM Incorporated - San Diego CA
International Classification:
G06F 12/06 G06F 13/372
US Classification:
711 5, 710244, 711E12082
Abstract:
Techniques are provided which may be implemented in various methods and/or apparatuses that to provide a memory pool interface capability to interface with a plurality of shared processes/engines and/or a virtual buffer interface associated there with.
System And Method For Confidentiality-Preserving Rank-Ordered Search
- College Park MD, US Yinian MAO - San Diego CA, US Hongmei GOU - Germantown MD, US Avinash VARNA - Greenbelt MD, US Shan HE - Plainsboro NJ, US Min WU - Clarksville MD, US Douglas W. OARD - College Park MD, US
A confidentiality preserving system and method for performing a rank-ordered search and retrieval of contents of a data collection. The system includes at least one computer system including a search and retrieval algorithm using term frequency and/or similar features for rank-ordering selective contents of the data collection, and enabling secure retrieval of the selective contents based on the rank-order. The search and retrieval algorithm includes a baseline algorithm, a partially server oriented algorithm, and/or a fully server oriented algorithm. The partially and/or fully server oriented algorithms use homomorphic and/or order preserving encryption for enabling search capability from a user other than an owner of the contents of the data collection. The confidentiality preserving method includes using term frequency for rank-ordering selective contents of the data collection, and retrieving the selective contents based on the rank-order.
Dr. Wu graduated from the Ross Univ, Sch of Med, Roseau, Dominica in 2002. He works in Turlock, CA and specializes in Family Medicine. Dr. Wu is affiliated with Emanuel Medical Center.
Jan 2011 to 2000 Risk Arbitrage AnalystHaver Analytics New York, NY Jul 2009 to Jan 2011 Senior Research AssociateIndustrial Bank Co., Ltd. - China Tianjian Aug 2007 to Jul 2008 Intern, Risk Management
Education:
Lubin School of Business New York, NY 2009 to 2010 Masters in Financial ManagementTianjin University of Finance and Economics - China 2003 to 2007 BS in Accounting
Skills:
Financial Modeling, Valuation, Data Management, Equity Analysis