Milan D Janic

US Patent:

53257138, Jul 5, 1994

Filed:

Apr 29, 1993

Appl. No.:

8/054631

Inventors:

Kenneth L. Furst - Appleton WI
Robert O. Dilmore - Ross Township, Allegheny County PA
Milan D. Janic - Columbus OH
Bozidar Stipanovic - Lake Forest IL

Assignee:

PPG Industries, Inc. - Pittsburgh PA

International Classification:

G01N 3334
G01B 1700

US Classification:

73150R

Abstract:

Described is apparatus and a method for measuring the integrity of coated paper, which apparatus comprises, a reservoir for a test liquid, e. g. , water, retaining means for holding a sample of coated paper which is in liquid communication with the test liquid reservoir, means for applying ultrasonic energy to the sample of coated paper, photoelectric means for continuously measuring the turbidity of the test liquid, the photoelectric means being in liquid communication with the test liquid reservoir and the paper sample, recording means electrically connected to the photoelectric means for continuously recording the turbidity measurements, and means, including pumping means, for circulating test liquid between the reservoir, photoelectric means and paper sample retaining device.

US Patent:

47676140, Aug 30, 1988

Filed:

Dec 16, 1986

Appl. No.:

6/942961

Inventors:

Ioannis S. Scarpa - Chicago IL
Andrew M. Chludzinski - Westmont IL
Milan D. Janic - River Forest IL

Assignee:

Wm. Wrigley Jr. Company - Chicago IL

International Classification:

A61K 968
A61K 716
A61K 3173
A61K 31735

US Classification:

424 48

Abstract:

The compounds of the present invention are linear and branched dextrans having a plurality of their glucose units modified at the 3-position ring carbon with groups selected from the class consisting of keto, amino, halo, benzyl, alkyl, sulfonyl, carboxyl and hydrogen. The modified dextrans reduce and/or modify activity of glucosyltransferase enzymes (GTF) which are produced by oral strains of Streptococcus mutans bacteria. GTF enzymes mediate oral biosynthesis of plaque-forming glucose polymers (glucans) from ingested sucrose. Therefore, the dextrans of the present invention, which reduce and/or modify activity of GTF enzymes, are useful in reducing the formation of dental plaque. The present invention is further directed to a dental health method comprising the step of contacting the oral cavity with linear or branched dextran compounds having a plurality of their glucose units modified at the 3-position carbon with a group such as keto, amino, halo, benzyl, alkyl, sulfonyl, carboxyl or hydrogen.

Author:

Milan Janic

ISBN #:

9056992449