Michael P. Murtaugh - Shoreview MN, US Craig R. Johnson - Lakeville MN, US
Assignee:
Regents of the University of Minnesota - Saint Paul MN
International Classification:
A61K 39/12
US Classification:
4242041, 435 6
Abstract:
This document provides methods and materials related to assessing organisms for the presence or absence of anti-virus antibodies. For example, this document provides methods and materials that can be used to determine whether or not an organism (e. g. , a member of a swine species such as a pig) contains anti-PRRS virus antibodies. In other embodiments, this document provides methods and materials that can be used to determine if a particular organism received a vaccine version of a virus, was infected with a naturally-occurring version of the virus, or is naive with respect to the virus.
Identifying Virally Infected And Vaccinated Organisms
Michael P. Murtaugh - Shoreview MN, US Craig R. Johnson - Eagan MN, US
Assignee:
Regents of the University of Minnesota - St. Paul MN
International Classification:
C12Q 1/70
US Classification:
435 5, 435 71
Abstract:
This document provides methods and materials related to assessing organisms for the presence or absence of anti-virus antibodies. For example, this document provides methods and materials that can be used to determine whether or not an organism (e. g. , a member of a swine species such as a pig) contains anti-PRRS virus antibodies. In other embodiments, this document provides methods and materials that can be used to determine if a particular organism received a vaccine version of a virus, was infected with a naturally-occurring version of the virus, or is naïve with respect to the virus.
Identifying Virally Infected And Vaccinated Organisms
Michael P. Murtaugh - Shoreview MN, US Craig R. Johnson - Eagan MN, US
Assignee:
REGENTS OF THE UNIVERSITY OF MINNESOTA - Saint Paul MN
International Classification:
C12Q 1/70
US Classification:
435 5
Abstract:
This document provides methods and materials related to assessing organisms for the presence or absence of anti-virus antibodies. For example, this document provides methods and materials that can be used to determine whether or not an organism (e.g., a member of a swine species such as a pig) contains anti-PRRS virus antibodies. In other embodiments, this document provides methods and materials that can be used to determine if a particular organism received a vaccine version of a virus, was infected with a naturally-occurring version of the virus, or is naïve with respect to the virus.
Anthony C. Caputa - Nanuet NY Russell F. Bey - Arden Hills MN Michael P. Murtaugh - Roseville MN
Assignee:
Regents of the University of Minnesota - Minneapolis MN
International Classification:
A61K 3900 A61K 3902 C12P 2100 C07K 1600
US Classification:
4242341
Abstract:
A highly-antigenic, recombinant polypeptide of a molecular weight of about 110-kD by SDS-PAGE is disclosed, which is derived by transforming E. coli with a 7. 1 kB DNA fragment from EcoR1-digested B. burgdorferi DNA, followed by identification of cloned transformants expressing polypeptides which bind to anti-B. burgdorferi antibodies.
Vr-2332 Viral Nucleotide Sequence And Methods Of Use
Michael P. Murtaugh - Roseville MN Margaret R. Elam - Minneapolis MN Laura T. Kakach - Hopkins MN
Assignee:
Regents of The University of Minnesota - Minneapolis MN
International Classification:
C07H 2104 A61K 3902 A61K 3912
US Classification:
536 2372
Abstract:
A nucleotide sequence is provided for the VR-2332 virus, which is capable of causing Porcine Reproductive and Respiratory Syndrome. The nucleotide sequence includes protein coding regions that are inserted into recombinant vectors for the host expression of viral proteins according to a variety of vaccination techniques. Diagnostic assays utilize fragmentary sequences or oligonucleotides to selectively identify the VR-2332 nucleic acids by hybridization or PCR amplification reactions that distinguish VR-2332 nucleotide sequences from other PRRS-causative viruses which are immunologically distinct from VR-2332.