Michael I Falkel

US Patent:

8303566, Nov 6, 2012

Filed:

Jul 9, 2010

Appl. No.:

12/833702

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I. Falkel - Carmel Highlands CA, US

Assignee:

Onpharma, Inc. - Los Gatos CA

International Classification:

A61M 5/32

US Classification:

604413, 604403, 604411

Abstract:

A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.

US Patent:

20080045925, Feb 21, 2008

Filed:

Jun 18, 2007

Appl. No.:

11/820208

Inventors:

Matthew Stepovich - Santa Cruz CA, US
Michael Falkel - Carmel Highlands CA, US
Kenneth Davenport - Fort Collins CO, US

International Classification:

A61M 31/00
A61M 37/00
A61M 5/44

US Classification:

604518000, 604113000, 604082000

Abstract:

System for the delivery of drugs from sealed cartridges provide for versatile and convenient delivery of the drugs. The system can be designed to deliver drugs from a plurality of cartridges with delivery through a manifold that connects to the plurality of cartridges. In some embodiments, the system mediates the heating of the drug such that it can be delivered at a temperature more closely approximating body temperature. In some embodiments, the composition of one cartridge is used to adjust the pH of the composition of the resulting mixture to achieve a desirable blended drug. The systems and procedures are particularly advantageous for the delivery of dental anesthetics.

US Patent:

20080086108, Apr 10, 2008

Filed:

Oct 4, 2007

Appl. No.:

11/973007

Inventors:

Michael I. Falkel - Carmel Highlands CA, US
Matthew J. Stepovich - Santa Cruz CA, US

International Classification:

A61M 5/31

US Classification:

604506, 604171

Abstract:

A device to facilitate the administration of an injection to a patient can comprise a hand piece that comprises of a core and a sheath. The core can comprise of a needle assembly and a thumb piece, and the sheath can enclose a portion of the core, at least in some configurations. In some embodiments, the hand piece can comprise of at least one releasable locking mechanism to enable the sheath to lock onto the core in different positions, particularly a safe position in which the needle assembly is enclosed within the sheath and an exposed position in which the needle is exposed from the sheath. A fluid connection within the core connects the needle assembly with a fluid source outside the core. The user can grip the hand piece by supporting their thumb on the thumb piece and positioning the hand piece between the user's two non-thumb fingers. Thus, the user can employ a traditional one-hand grip corresponding to the use of a manual dental syringe. To unlock the sheath of the hand piece, one of the user's non-thumb fingers can be positioned near the locking mechanism to provide ready release of the locking mechanism such that movement of the sheath relative to the needle assembly can occur to expose the needle for an injection into the patient. After delivery of a drug, the sheath can be moved to enclose the needle for later use or disposal.

US Patent:

20090292271, Nov 26, 2009

Filed:

Mar 18, 2009

Appl. No.:

12/406670

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I. Falkel - Carmel Highlands CA, US

Assignee:

Monterey Devices, Inc. - Soquel CA

International Classification:

A61J 1/20

US Classification:

604414, 604415

Abstract:

A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage.

US Patent:

20110005958, Jan 13, 2011

Filed:

Apr 23, 2010

Appl. No.:

12/766259

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I. Falkel - Carmel Highlands CA, US
Harry Nguyen - Westminster CA, US

Assignee:

Onpharma, Inc. - Los Gatos CA

International Classification:

B65D 85/84
B67C 3/22
B65D 25/00

US Classification:

2065241, 53428, 53111 R, 220737

Abstract:

Buffer solutions within a plurality of containers can be adjusted and controlled by exposing the containers while open to a controlled environment. In particular, an inventory of containers holding bicarbonate buffers can be adjusted to a precisely controlled pH by exposing the containers while open to a controlled carbon dioxide environment in a treatment chamber.

US Patent:

20110247722, Oct 13, 2011

Filed:

Apr 7, 2011

Appl. No.:

13/082260

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I. Falkel - Carmel Highlands CA, US

Assignee:

Onpharma, Inc. - Los Gatos CA

International Classification:

B65B 1/04
B65D 85/00

US Classification:

141 2, 141 18, 2065241

Abstract:

An anesthetic cartridge is adapted to receive a volume of buffer by displacing a plunger in one end of the anesthetic cartridge inwardly so that addition of the buffer volume will not displace the plunger excessively beyond the end of the cartridge body. By properly determining the amount of buffer volume required to raise the pH of the anesthetic to a target value, the degree of inward displacement of the plunger can be determined and the cartridge can be used with a system for delivering a precise amount of buffer solution having a known pH into the cartridge to raise its pH, just before the anesthetic is delivered to the patient.

US Patent:

20110282316, Nov 17, 2011

Filed:

Nov 11, 2010

Appl. No.:

12/944492

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I. Falkel - Carmel Highlands CA, US
Harry Nguyen - Westminster CA, US

Assignee:

Onpharma Inc. - Los Gatos CA

International Classification:

A61J 1/20
A61J 1/14

US Classification:

604414, 604416

Abstract:

A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage. By delivering a buffer with a precisely controlled pH, accurate buffering of the anesthetic can be achieved.

US Patent:

20120180432, Jul 19, 2012

Filed:

Mar 23, 2012

Appl. No.:

13/428283

Inventors:

Matthew J. Stepovich - Santa Cruz CA, US
Michael I Falkel - Carmel Highlands CA, US

Assignee:

Onpharma, Inc. - Los Gatos CA

International Classification:

B67C 3/22
B65D 85/84

US Classification:

53428, 2065241

Abstract:

A device for delivering buffer solution into a buffer cartridge comprises a needle assembly and a pusher. The septa of a buffer cartridge and an anesthetic cartridge are advanced onto a transfer needle, and the pusher advances a plunger into the buffer cartridge to deliver buffer through the transfer needle into the anesthetic cartridge. A separate exhaust needle allows excess anesthetic from the anesthetic cartridge to be exhausted. A compression member is usually provided to maintain a force against the plunger on the buffer cartridge to pressurize and stabilize the contents during sterilization and/or storage.