Clinical Research • Medical Education • Clinical Trials • Animal Models • Lifesciences • Immunohistochemistry • Immunology • Cell Biology • Cancer • Flow Cytometry • Life Sciences • Genetics • Western Blotting • In Vitro • Cancer Research • In Vivo • Molecular Biology • Cell Culture
University of Nebraska Medical Center
Research Coordinator
Education:
University of Nebraska Medical Center 1996 - 2000
Master of Science, Masters, Immunology
Doane University 1991 - 1995
Bachelors, Bachelor of Science, Biology
Skills:
Clinical Research Medical Education Clinical Trials Animal Models Lifesciences Immunohistochemistry Immunology Cell Biology Cancer Flow Cytometry Life Sciences Genetics Western Blotting In Vitro Cancer Research In Vivo Molecular Biology Cell Culture
In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde acetaldehyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction.
- Lincoln NE, US Daniel R. ANDERSON - Omaha NE, US Michael J. DURYEE - Omaha NE, US
International Classification:
G01N 33/53 A61K 49/00 G01N 33/564
Abstract:
In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldheyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction.
In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldehyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction.