Xiaomei Feng - Waltham MA, US Huiping Guan - Waltham MA, US Ying Kang - Shanghai, CN Stephanos Ioannidis - Waltham MA, US Bo Peng - Waltham MA, US Mei Su - Waltham MA, US Bin Wang - Longmont CO, US Tao Wang - Waltham MA, US Hai-Jun Zhang - Waltham MA, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
C07D 403/14 A61K 31/506
US Classification:
514275, 544296
Abstract:
This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
9-(Pyrazol-3-Yl)-9H-Purine-2-Amine And 3-(Pyrazol-3-Yl) -3H-Imidazo[4,5-B] Pyridin-5-Amine Derivatives And Their Use For The Treatment Of Cancer
Audrey Davies - Waltham MA, US Stephanos Ioannidis - Waltham MA, US Michelle Lamb - Waltham MA, US Mei Su - Waltham MA, US Tao Wang - Waltham MA, US Hai-Jun Zhang - Waltham MA, US
The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.
Susan Ashwell - Waltham, GB Thomas Gero - Waltham MA, US Stephanos Ioannidis - Watham MA, US James Janetka - Waltham MA, US Paul Lyne - Waltham MA, US Vibha Oza - Waltham MA, US Stephanie Springer - Cambridge MA, US Mei Su - Waltham MA, US Dingwei Yu - Waltham MA, US
International Classification:
A61K 31/00
US Classification:
514001000
Abstract:
This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
Susan Ashwell - Waltham MA, US Jayachandran Ezhuthachan - Waltham MA, US Paul Lyne - Waltham MA, US Nicholas Newcombe - Cheshire, GB Martin Pass - Cheshire, GB Vibha Oza - Waltham MA, US Mei Su - Waltham MA, US Dorin Toader - Waltham MA, US Dingwei Yu - Waltham MA, US Yan Yu - Waltham MA, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 31/4745 C07D 487/02
US Classification:
514292000, 546082000
Abstract:
This invention relates to novel compounds having the structural diagram (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
4-(3-Aminopyrazole) Pyrimidine Derivatives For Use As Tyrosine Kinase Inhibitors In The Treatment Of Cancer
Xiaomei Feng - Waltham MA, US Huiping Guan - Waltham MA, US Ying Kan - Shanghai, CN Stephanos Ioannidis - Waltham MA, US Bo Peng - Waltham MA, US Mei Su - Waltham MA, US Bin Wang - Longmont CO, US Tao Wang - Waltham MA, US Hai-Jun Zhang - Waltham MA, US
Assignee:
ASTRAZENECA AB - Sodrtalje
International Classification:
A61K 31/506 A61P 35/00 C07D 403/14 C07D 413/14
US Classification:
514272, 544296, 544122, 514275, 514269
Abstract:
This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
Susan Ashwell - Waltham MA, US Thomas Gero - Waltham MA, US Stephanos Ioannidis - Waltham MA, US James Janetka - Waltham MA, US Paul Lyne - Waltham MA, US Vibha Oza - Waltham MA, US Mei Su - Waltham MA, US Dingwei Yu - Waltham MA, US Stephanie Springer - North Andover MA, US
This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
Tricyclic 2,4-Diamino-L,3,5-Triazine Derivatives Useful For The Treatment Of Cancer And Myeloproliferative Disorders
Lynsie Almeida - Waltham MA, US Claudio Edmundo Chuaqui - Waltham MA, US Stephanos Loannidis - Waltham MA, US Bo Peng - Waltham MA, US Mei Su - Waltham MA, US
The present invention relates to compounds of Formula (I): (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.
Claudio Edmundo Chuaqui - Waltham MA, US Shan Huang - Waltham MA, US Stephanos Ioannidis - Waltham MA, US Jie Shi - Waltham MA, US Mei Su - Waltham MA, US Qibin Su - Waltham MA, US
The present invention relates to compounds of Formula (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.