Matthias Dr Kretschmer

age ~69

from Brookline, MA

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Also known as:

Matthias Werner Kretschmer
Matthias W Kretschmer
Matthias M Kretschmer
Matthias Kretschmer Dr
Matthias W Kretscmer
Matt Kretschmer
Metthias Kretschmer
Matthias Kretchmer

Phone and address:: 32 Dwight St, Brookline, MA 02446

Connected to:

Matthias Kretschmer Phones & Addresses

32 Dwight St, Brookline, MA 02446
20 Alden Rd, West Yarmouth, MA 02673
9 Hastings Rd, Weston, MA 02493 • 781 891-5105
12 Viles St, Weston, MA 02493 • 781 891-5105

Work

Company:

Alnylam pharmaceuticals
2008
Position:

Director analytical sciences

Industries

Biotechnology

Resumes

Matthias Kretschmer

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Position:

Director Analytical Sciences at Alnylam Pharmaceuticals

Location:

Greater Boston Area

Industry:

Biotechnology

Work:

Alnylam Pharmaceuticals since 2008
Director Analytical Sciences

Us Patents

Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis
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US Patent:

20070275481, Nov 29, 2007
Filed:

Nov 23, 2004
Appl. No.:

10/579639
Inventors:

Elena Vasilyeva - Swampscott MA, US
Francine Brown - Amherst NH, US
Matthias Kretschmer - Weston MA, US
Peter Bove - Burlington VT, US
Hans Fajardo - Wakefield MA, US
Frederick Taylor - Milton MA, US
Rohin Mhatre - Lexington MA, US
Kazumi Kobayashi - Arlington MA, US
Amy Dingley - Roslindale MA, US
Assignee:

BIOGEN IDEC MA INC. - CAMBRIDGE MA
International Classification:

G01N 33/561
C07K 1/00
C07K 14/00
C07K 16/18
G01N 33/00
US Classification:

436516000, 436086000, 530350000, 530387100, 530409000
Abstract:

The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibodies. The invention further features a kit, comprising a chip, and instructions for conducting the foregoing method. The methods and kits of the invention are amendable to high throughput applications for the monitoring of production and quality control of recombinant therapeutic antibodies.

Methods For Detecting Half-Antibodies Using Chip-Based Gel Electrophoresis
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US Patent:

20050176157, Aug 11, 2005
Filed:

Dec 19, 2002
Appl. No.:

10/499259
Inventors:

Elena Vasilyeva - Swampscott MA, US
Matthias Kretschmer - Weston MA, US
Peter Bove - Burlington VT, US
Francine Brown - Westford MA, US
International Classification:

G01N033/561
US Classification:

436516000
Abstract:

The invention provides a method of using chip-based gel electrophoresis to determine the presence of polypeptides with selected disulfide linkage patterns, for example, completely formed tetrameric antibodies as compared to incompletely formed heterodimeric half-antibodies. The invention further features a kit, comprising a chip, and instructions for conducting the foregoing method. The methods and kits of the invention are amendable to high throughput applications for the monitoring of production and quality control of recombinant therapeutic antibodies.

Name / Title

Company / Classification

Phones & Addresses

Matthias Kretschmer
Director Analytical Sciences

Alnylam Pharmaceuticals
Biotechnology · Biopharmaceutical Research · Commercial Physical Research · Biotechnical Research & Pharmaceutical Preparations · Mfg of Pharmaceutical Preparations and Biotechnical Research · Mfg Pharmaceutical Preparations and Biotechnical Research · Pharmaceutical Preparation Mfg

300 3 St, Cambridge, MA 02142
617 551-8200, 617 551-8101, 617 252-0700