Mary K. Willian - Scottsdale AZ, US Martin M. Okun - Wilmette IL, US Rebecca S. Hoffman - Wilmette IL, US Yihua Gu - Vernon Hills IL, US Lisa Melilli - Norwalk CT, US Kenneth B. Gordon - Northbrook IL, US
International Classification:
A61B 5/00 A61K 39/395 C07K 16/24
US Classification:
424 98, 4241331, 5303873
Abstract:
The invention provides methods, uses and compositions for the treatment of psoriasis. The invention describes methods and uses for treating psoriasis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment psoriasis in a subject.
Uses And Compositions For Treatment Of Psoriasis And Crohn's Disease
MARTIN M. OKUN - Libertyville IL, US REBECCA S. HOFFMAN - WILMETTE IL, US THOMAS C. HARRIS - GURNEE IL, US PARVEZ M. MULANI - GURNEE IL, US JINGDONG CHAO - LAKE BLUFF IL, US Talat Ashraf - Pleasanton CA, US
International Classification:
A61K 39/395 G06F 19/00 G06F 17/18
US Classification:
4241331, 4241581, 4241411, 702 19, 702179
Abstract:
The invention provides methods, uses and compositions for the treatment of psoriasis or Crohn's disease. The invention describes methods and uses for treating psoriasis or Crohn's disease, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. The invention includes methods of improving patient reported outcomes using a human TNFα antibody, or antigen-binding portion thereof, for the treatment of Crohn's or psoriasis. The invention also provides methods of improving fatigue or depression in patients having Crohns'.
Methods And Compositions For Treatment Of Skin Disorders
Martin M. Okun - Libertyville IL, US Rebecca S. Hoffman - Wilmette IL, US Jonathan Barker - London, GB
International Classification:
A61K 39/395 A61K 39/00 A61P 17/06
US Classification:
4241421, 4241581, 4241841
Abstract:
The invention provides methods and compositions for the treatment of a skin disorder associated with detrimental TNFα activity, such as psoriasis. The invention includes methods for treating a skin disorder associated with detrimental TNFα activity, such as psoriasis, in a subject who has failed or lost response to prior biologic therapy, such as prior administration of etanercept. The invention further provides methods for determining the efficacy of a human TNFα antibody, or antigen-binding portion thereof, for the treatment of a skin disorder associated with detrimental TNFα activity, such as psoriasis.
Uses And Compositions For Treatment Of Hidradenitis Suppurativa (Hs)
Martin M. OKUN - Libertyville IL, US Thomas C. Harris - Gurnee IL, US
International Classification:
A61K 39/395 A61P 17/00 B65D 71/00 A61P 29/00
US Classification:
4241421, 4241581, 206570
Abstract:
The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treating hidradenitis suppurativa in a subject.
Uses And Compositions For Treatment Of Psoriasis And Crohn's Disease
Martin M. Okun - Libertyville IL, US Rebecca S. Hoffman - Wilmette IL, US Thomas C. Harris - Gurnee IL, US Parvez M. Mulani - Gurnee IL, US Jingdong Chao - Lake Bluff IL, US Talat Ashraf - Pleasanton CA, US
International Classification:
G06F 19/24 A61P 1/00 A61K 39/395
US Classification:
4241421, 702 19
Abstract:
The invention provides methods, uses and compositions for the treatment of psoriasis or Crohn's disease. The invention describes methods and uses for treating psoriasis or Crohn's disease, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. The invention includes methods of improving patient reported outcomes using a human human TNFα antibody, or antigen-binding portion thereof, for the treatment of Crohn's or psoriasis. The invention also provides methods of improving fatigue or depression in patients having Crohns'.
Joaquin Mario Valdes - Mundelein IL, US Elliot K. Chartash - Marietta GA, US William T. Barchuk - San Diego CA, US Susan K. Paulson - Downers Grove IL, US Kenneth B. Gordon - Northbrook IL, US Walid M. Awni - Green Oaks IL, US Yanjun Bao - Buffalo Grove IL, US William G. Glass - Libertyville IL, US Yihua Gu - Vernon Hills IL, US Thomas C. Harris - Gurnee IL, US Martin Kaul - Neustadt, DE Parvez M. Mulani - Gurnee IL, US Peter A. Noertersheuser - Grosskarlbach, DE Martin M. Okun - Libertyville IL, US
International Classification:
C07K 16/24
US Classification:
4241421, 4241581
Abstract:
The invention provides methods of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23.
Methods For Treating Psoriasis Using Antibodies That Bind To The P40 Subunit Of Il-12 And/Or Il-23
Joaquin Mario Valdes - Mundelein IL, US Elliot K. Chartash - Marietta GA, US William T. Barchuk - San Diego CA, US Susan K. Paulson - Downers Grove IL, US Kenneth B. Gordon - Northbrook IL, US Walid M. Awni - Green Oaks IL, US Yanjun Bao - Buffalo Grove IL, US William G. Glass - Libertyville IL, US Yihua Gu - Vernon Hills IL, US Tom C. Harris - Gurnee IL, US Martin Kaul - Neustadt, DE Parvez M. Mulani - Gurnee IL, US Peter Noertersheuser - Grosskarlbach, DE Martin M. Okun - Libertyville IL, US
Assignee:
AbbVie Inc. - North Chicago IL AbbVie Deutschland GmbH & Co. KG - Wiesbaden
The invention provides methods of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23.
- Hamilton, BM Martin M. Okun - Wilmette IL, US Rebecca S. Hoffman - Wilmette IL, US Yihua Gu - Vernon Hills IL, US Lisa E. Melilli - Norwalk CT, US Kenneth B. Gordon - Northbrook IL, US
International Classification:
C07K 16/24
Abstract:
The invention provides methods, uses and compositions for the treatment of psoriasis. The invention describes methods and uses for treating psoriasis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriasis in a subject.
Resumes
Medical Director, Clinical Development At Abbott Laboratories