Martha Jo Morrell

Author:

Martha Morrell

ISBN #:

0521652243

Author:

Martha Morrell

ISBN #:

0521655412

US Patent:

7813811, Oct 12, 2010

Filed:

Feb 8, 2007

Appl. No.:

11/704534

Inventors:

Brett M. Wingeier - San Francisco CA, US
Martha J. Morrell - Atherton CA, US
C. Lance Boling - San Jose CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/00

US Classification:

607116

Abstract:

Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

US Patent:

7844345, Nov 30, 2010

Filed:

Feb 8, 2007

Appl. No.:

11/704549

Inventors:

C. Lance Boling - San Jose CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Atherton CA, US
Benjamin D. Pless - Mountain View CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/00

US Classification:

607116

Abstract:

Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e. g. , by a substantial portion of the area of the substrate). Examples of bioactive agents that may be used in the lead system include antiproliferative agents, bactericidal agents, bacteriostatic agents, antiepileptic agents, and/or antifungal agents. Methods described herein may comprise coating a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.

US Patent:

8160720, Apr 17, 2012

Filed:

Sep 13, 2010

Appl. No.:

12/881171

Inventors:

Brett M. Wingeier - San Francisco CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/00

US Classification:

607116

Abstract:

Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

US Patent:

8190270, May 29, 2012

Filed:

Jan 10, 2012

Appl. No.:

13/347675

Inventors:

Brett M. Wingeier - San Francisco CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/00

US Classification:

607116

Abstract:

Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.

US Patent:

8423156, Apr 16, 2013

Filed:

Feb 9, 2012

Appl. No.:

13/370269

Inventors:

C. Lance Boling - San Jose CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Portola Valley CA, US
Benjamin D. Pless - Atherton CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/00

US Classification:

607116

Abstract:

Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e. g. , by a substantial portion of the area of the substrate). Methods described herein may comprise contacting the substrate of a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.

US Patent:

20060058856, Mar 16, 2006

Filed:

Sep 14, 2004

Appl. No.:

10/941759

Inventors:

Martha Morrell - Portola Valley CA, US

Assignee:

NeuroPace, Inc. - Mountain View CA

International Classification:

A61N 1/34

US Classification:

607046000

Abstract:

An implantable neurostimulator system for treating psychiatric disorders includes scheduled and responsive therapy capabilities including responsive stimulation applied to the cingulate gyrus of the brain. Methods for treating depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders employ an inventive system to advantageously reduce symptoms and address underlying causes of the disorders.

US Patent:

20080077191, Mar 27, 2008

Filed:

Sep 21, 2006

Appl. No.:

11/525586

Inventors:

Martha J. Morrell - Atherton CA, US

International Classification:

A61N 1/00

US Classification:

607 45

Abstract:

Methods of treating language, behavioral and social disorders are described, including methods of treating language disorders associated with electrographic abnormalities in the primary or associative language cortex of persons with autism spectrum disorders, pervasive developmental delay or acquired epileptic aphasia. A language, behavioral and social disorder may be treated by detecting epileptiform activity or an electrographic seizure for a subject's brain and applying neurostimulation to a language cortical region of the subject's brain (e.g., a primary or associative language cortical region). Detection of epileptiform activity or an electrographic seizure and stimulation of language cortex may be performed by a sensing and/or stimulation electrode that is inserted into a subject's brain and connected to one or more neurostimulation devices for monitoring and/or stimulating the language cortex.

US Patent:

20080125830, May 29, 2008

Filed:

Feb 8, 2008

Appl. No.:

12/028625

Inventors:

Martha Morrell - Portola Valley CA, US

Assignee:

NEUROPACE, INC. - Mountain View CA

International Classification:

A61N 1/05

US Classification:

607 45

Abstract:

An implantable medical device is capable of delivering a form of therapy (e.g., electrical stimulation) to a region of the cingulate cortex of a patient's brain to treat a neurological event, condition or disorder, especially an event, condition, or disorder that is psychiatric in nature, such as depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders. The apparatus is also capable of detecting a signal corresponding to a characteristic of the psychiatric disorder. Methods of using the apparatus are also disclosed.