Mark H. Krackov - Wilmington DE Charles H. Rolston - Woodbury NJ
Assignee:
E. I. Du Pont De Nemours and Company - Wilmington DE
International Classification:
C07C 1722 C07C 2513
US Classification:
570141
Abstract:
Process which comprises feeding an aromatic amine in the presence of HF to a reaction zone simultaneously with a diazotizing agent so as to effect diazotization of the aromatic amine, thermally decomposing the resulting diazonium salt substantially as it is formed, and removing the resulting fluoroaromatic compound from the reaction zone substantially as it is formed. The amine and the diazotizing agent are fed to the reaction zone in such quantities and proportions that they are consumed substantially as fed so that no substantial concentration of either builds up in the reaction zone.
Process For The Synthesis Of Curcumin-Related Compounds
Mark Harry Krackov - West Chester PA Harold Edward Bellis - Wilmington DE
Assignee:
Gene Print Inc. - Bala Cynwyd PA
International Classification:
C07C 4500
US Classification:
568313
Abstract:
The invention is directed to a process for the synthesis of curcumin and curcumin-related compounds by reacting the enol form of a 2,4-diketone with a monocarbocyclic aldehyde in the presence of an organic amine catalyst. The reactants are dissolved in a highly polar, aprotic organic solvent. The curcumin-related product is recovered in crystalline form by precipitation from the reaction mass and solvent recrystallization.
Richard E. Fernandez - Bear DE Mark H. Krackov - West Chester PA
Assignee:
E. I. Du Pont de Nemours and Company - Wilmington DE
International Classification:
C07C 1720
US Classification:
568932
Abstract:
A process for halogen exchange fluorination or fluoro-denitration of aromatic compounds having at least one replaceable non-fluorine halogen or nitro substituent with an anhydrous substantially molten alkali metal acid fluoride composition wherein the alkali metal is potassium, rubidium or cesium.
Process For Making Water-Soluble Derivatives Of Quinones
Process for making water-soluble hydroquinone salts by reacting an aqueous liquid solution of (a) a formamidinesulfinic acid and (b) an alkali metal or quaternary ammonium hydroxide in which is dispersed a (c) quinone and water-soluble hydroquinone salts made thereby.