Mark R Etzel

US Patent:

7378123, May 27, 2008

Filed:

May 6, 2005

Appl. No.:

11/123960

Inventors:

Mark R. Etzel - Madison WI, US
Thomas R. Helm - Oshkosh WI, US
Harit K. Vyas - Fond du Lac WI, US

Assignee:

Wisconsin Alumni Research - Madison WI
Grande Cheese Company - Lomira WI

International Classification:

A23J 1/00

US Classification:

426656, 426583, 426491, 426495

Abstract:

The present invention concerns methods and compositions that involve whey protein isolates. Methods of the invention include purification processes for preparing whey proteins that are substantially nondenatured across a range of pH, including their isoelectric points. As such, they have low turbidity in solution across a wide range of pH values. Whey protein isolates can be integrated into compositions and solutions that have nutritional, pharmaceutical, and other applications.

US Patent:

7750117, Jul 6, 2010

Filed:

Feb 11, 2004

Appl. No.:

10/777825

Inventors:

Mark E. Cook - Madison WI, US
Mingder Yang - Madison WI, US
Mark R. Etzel - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

C07K 16/02

US Classification:

530350, 530359, 5303871, 426 55

Abstract:

It is disclosed here that a protein with a heat-labile specific binding activity can be stabilized with a saccharide compound with regard to the binding activity. To heat-stabilize the protein, it is mixed with a saccharide compound in a liquid suspension and the suspension is then dried to produce a solid that contains the protein and the saccharide. The saccharide compounds that possess the protein heat-stabilization activity include monosaccharides, disaccharides, polysaccharides, alkylated monosaccharides, alkylated disaccharides, alkylated polysaccharides, monosaccharide alcohols and alkylated monosaccharide alcohols.

US Patent:

8071152, Dec 6, 2011

Filed:

Apr 30, 2008

Appl. No.:

12/112607

Inventors:

Mark R. Etzel - Madison WI, US
Thomas R. Helm - Oshkosh WI, US
Harit K. Vyas - Fond du Lac WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI
Grande Cheese Company - Brownsville WI

International Classification:

A23C 9/146

US Classification:

426656, 426583, 426491, 426495, 426271

Abstract:

The present invention concerns methods and compositions that involve whey protein isolates. Methods of the invention include purification processes for preparing whey proteins that are substantially nondenatured across a range of pH, including their isoelectric points. As such, they have low turbidity in solution across a wide range of pH values. Whey protein isolates can be integrated into compositions and solutions that have nutritional, pharmaceutical, and other applications.

US Patent:

8586338, Nov 19, 2013

Filed:

May 27, 2009

Appl. No.:

12/993265

Inventors:

Mark R. Etzel - Madison WI, US
Yi He - Roseville MN, US
Steven M. Heilmann - Afton MN, US
Jerald K. Rasmussen - Woodville MN, US
Kannan Seshadri - Woodbury MN, US
Simon K. Shannon - Horseheads NY, US
Douglas E. Weiss - Golden Valley MN, US

Assignee:

3M Innovative Properties Company - St. Paul MN
Wisconsin Alumni Research Foundation - Madison WI

International Classification:

C12N 9/00
C12N 9/96
C12N 7/06
C08C 19/22

US Classification:

435191, 525376, 525379, 525381, 525382, 526310, 530421, 530412, 536 254, 435183, 435239, 4352521, 435261, 435325, 210679, 210735, 428582

Abstract:

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

US Patent:

8604168, Dec 10, 2013

Filed:

Jun 11, 2010

Appl. No.:

12/813988

Inventors:

Denise M. Ney - Brooklyn WI, US
Mark R. Etzel - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

A61K 38/16
A61K 35/20

US Classification:

530360, 530395, 514 55, 562575, 562560

Abstract:

Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.

US Patent:

20080014625, Jan 17, 2008

Filed:

Jul 12, 2007

Appl. No.:

11/776774

Inventors:

Mark R. Etzel - Madison WI, US

International Classification:

C12N 7/02

US Classification:

435239

Abstract:

A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.

US Patent:

20100075131, Mar 25, 2010

Filed:

Sep 18, 2009

Appl. No.:

12/562573

Inventors:

Mark R. Etzel - Madison WI, US
Kannan Seshadri - Woodbury MN, US
Jerald K. Rasmussen - Woodville WI, US
Douglas E. Weiss - Golden Valley MN, US
Yi He - Roseville MN, US

International Classification:

B32B 27/00
C08G 73/02
B05D 3/10

US Classification:

4283155, 528424, 4283193, 428376, 525 542, 525417, 427 213

Abstract:

Polyethyleneimine and polyalkylene biguanide ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

US Patent:

20120029165, Feb 2, 2012

Filed:

Jul 12, 2011

Appl. No.:

13/181234

Inventors:

Mark R. Etzel - Madison WI, US
Thatcher Root - Madison WI, US
Abhiram Arunkumar - Madison WI, US
Seyhun Gemili - Madison WI, US

International Classification:

C07K 1/36

US Classification:

530322, 530414, 530366, 530394

Abstract:

The present invention concerns methods of isolating milk proteins. Methods of the invention include charged ultrafiltration processes that use variations in pH to further separate protein species.