Manpreet S Wadhwa

US Patent:

8338374, Dec 25, 2012

Filed:

Dec 13, 2004

Appl. No.:

10/583923

Inventors:

Manpreet S Wadhwa - Thousand Oaks CA, US
Sandeep Nema - St. Louis MO, US
Advait Badkar - Wildwood MO, US

Assignee:

Pharmacia Corporation - St. Louis MO

International Classification:

A61K 38/27
A61K 38/17
A61K 38/18
A61K 47/42

US Classification:

514 114, 4241981, 424497, 530351

Abstract:

The present invention is directed to stable liquid growth hormone formulations that remain stable after physical agitation, and after exposure to one or more freeze-thaw events. Formulations of the present invention can be stored long term at a variety of temperatures, even frozen. In the present invention, a combination of buffer and stabilizing agents, including a non-ionic surfactant (e. g. , polysorbate 20), a polymer stabilizer (e. g. , polyethylene glycol), and other optional stabilizers combine to provide unexpected stability to aqueous formulations of a growth hormone (e. g. , human growth hormone).

US Patent:

20190223487, Jul 25, 2019

Filed:

Apr 5, 2019

Appl. No.:

16/376840

Inventors:

- Newbury Park CA, US
Manpreet S. WADHWA - Thousand Oaks CA, US

International Classification:

A23L 33/16
C02F 1/68
A23L 2/52

Abstract:

Liquid dietary supplement formulation compositions that provide dietary minerals and additional optional ingredients beneficial for health; methods for manufacturing such compositions; and methods for enabling convenient oral ingestion of the formulation ingredients, by adding the same to drinking water, beverages, foods, or meals. The inventive formulation compositions generally include water, water-soluble calcium compound(s), water-soluble magnesium compound(s), and additional optional ingredients, wherein the sum of the concentrations of the calcium and magnesium compounds is most preferably 2 molar or more, up to the point of saturation. The inventive formulation compositions possess inherent resistance to microbial growth. The inventive formulation compositions and variations thereof can be used as dietary supplements to increase take of beneficial minerals, to mineralize water, to fortify foods or beverages, and can also be used to prepare a variety of additional liquid formulations by varying the calcium and magnesium compounds, and/or by adding one or more compatible ingredient(s).

US Patent:

20140161955, Jun 12, 2014

Filed:

Dec 12, 2012

Appl. No.:

13/712328

Inventors:

Manpreet S. Wadhwa - Thousand Oaks CA, US

International Classification:

A23L 1/304

US Classification:

426590, 426648

Abstract:

This invention relates to liquid dietary supplement formulation compositions that provide dietary minerals and additional optional ingredients beneficial for health; methods of design and manufacture of such compositions; and methods to enable convenient oral ingestion of the formulation ingredients, by adding the formulations to drinking water, beverages, foods, or meals. The formulation compositions of this invention generally include water, water-soluble calcium compound(s), water-soluble magnesium compound(s), and additional optional ingredients, wherein the sum of the concentrations of the calcium and magnesium compounds is most preferably 2 molar or more, up to the point of saturation. The formulations of this invention possess inherent resistance to microbial growth. The formulations of this invention and variations thereof can be used as dietary supplements to increase intake of beneficial minerals, to mineralize water, to fortify foods or beverages, and can also be used to prepare a variety of additional liquid formulations by varying the calcium and magnesium compounds, and/or by adding one or more compatible ingredient(s).