John F. Engelhardt - Iowa City IA, US Weihong Zhou - Iowa City IA, US Maged M. Harraz - Iowa City IA, US Jennifer J. Marden - Iowa City IA, US
International Classification:
G01N 33/573
US Classification:
435 771
Abstract:
Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.
Method Of Identifying Compounds Useful To Treat Neuronal Degenerative Diseases
John F. Engelhardt - Iowa City IA, US Weihong Zhou - Iowa City IA, US Maged M. Harraz - Iowa City IA, US Jennifer J. Marden - Iowa City IA, US
International Classification:
G01N 33/53
US Classification:
435 78
Abstract:
Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.
Method Of Identifying Compounds Useful To Treat Neuronal Degenerative Diseases
Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.
Providing Sensory Stimulations Via Photoacoustic, Piezo-Based, Thermal, And/Or Electrical Effects
- Baltimore MD, US Peter GEHLBACH - Monkton MD, US James SPICER - Baltimore MD, US Jeeun KANG - Baltimore MD, US Maged HARRAZ - Ellicott City MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61F 9/08 A61N 5/06 A61N 7/00
Abstract:
A device may include an image capturing component to obtain images of an environment of a user, and a light projection system. The light projection system may include a laser source and an optical imager. The device may process, in real-time, images captured by the image capturing component to derive signals for controlling the laser source, provide the signals to the laser source to enable the laser source to generate a laser beam pattern, cause the optical imager to raster scan the laser beam pattern to an absorptive element. The absorptive element may be disposed on or in the user, and positioned proximate to a region-of interest, of the user, that includes neuronal cells. The laser beam pattern may cause the absorptive element to produce acoustic energy that cause depolarization of the neuronal cells. The sensory stimulation may enable the user to visually and/or auditorily perceive the environment.
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