Maged M Harraz from Ellicott City, MD, age 55

Method Of Identifying Compounds Useful To Treat Neuronal Degenerative Diseases
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US Patent:

20080206792, Aug 28, 2008
Filed:

Aug 7, 2007
Appl. No.:

11/890779
Inventors:

John F. Engelhardt - Iowa City IA, US
Weihong Zhou - Iowa City IA, US
Maged M. Harraz - Iowa City IA, US
Jennifer J. Marden - Iowa City IA, US
International Classification:

G01N 33/573
US Classification:

435 771
Abstract:

Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.

Method Of Identifying Compounds Useful To Treat Neuronal Degenerative Diseases
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US Patent:

20090239243, Sep 24, 2009
Filed:

Aug 7, 2007
Appl. No.:

11/890775
Inventors:

John F. Engelhardt - Iowa City IA, US
Weihong Zhou - Iowa City IA, US
Maged M. Harraz - Iowa City IA, US
Jennifer J. Marden - Iowa City IA, US
International Classification:

G01N 33/53
US Classification:

435 78
Abstract:

Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.

Method Of Identifying Compounds Useful To Treat Neuronal Degenerative Diseases
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US Patent:

20070265350, Nov 15, 2007
Filed:

Dec 28, 2006
Appl. No.:

11/617491
Inventors:

John Engelhardt - Iowa City IA, US
Weihong Zhou - Iowa City IA, US
Maged Harraz - Iowa City IA, US
Jennifer Marden - Iowa City IA, US
Assignee:

UNIVERSITY OF IOWA RESEARCH FOUNDATION - IOWA CITY IA
International Classification:

A61K 31/122
A61P 25/00
C07K 14/00
G01N 33/53
G01N 33/567
US Classification:

514689000, 435007200, 435007800, 530300000, 530324000, 530350000
Abstract:

Methods of identifying agents that inhibit ROS by altering the binding of a GTPase such as Rac to SOD, agents identified by the method, and methods of using compounds that inhibit ROS to inhibit or treat neuronal degenerative diseases, are provided.

Providing Sensory Stimulations Via Photoacoustic, Piezo-Based, Thermal, And/Or Electrical Effects
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US Patent:

20230100414, Mar 30, 2023
Filed:

May 10, 2018
Appl. No.:

16/612257
Inventors:

- Baltimore MD, US
Peter GEHLBACH - Monkton MD, US
James SPICER - Baltimore MD, US
Jeeun KANG - Baltimore MD, US
Maged HARRAZ - Ellicott City MD, US
Assignee:

The Johns Hopkins University - Baltimore MD
International Classification:

A61F 9/08
A61N 5/06
A61N 7/00
Abstract:

A device may include an image capturing component to obtain images of an environment of a user, and a light projection system. The light projection system may include a laser source and an optical imager. The device may process, in real-time, images captured by the image capturing component to derive signals for controlling the laser source, provide the signals to the laser source to enable the laser source to generate a laser beam pattern, cause the optical imager to raster scan the laser beam pattern to an absorptive element. The absorptive element may be disposed on or in the user, and positioned proximate to a region-of interest, of the user, that includes neuronal cells. The laser beam pattern may cause the absorptive element to produce acoustic energy that cause depolarization of the neuronal cells. The sensory stimulation may enable the user to visually and/or auditorily perceive the environment.