Lyudmila G Burdelya from Sarasota, FL, age 62

Method For Reducing The Effects Of Chemotherapy Using Flagellin Related Polypeptides
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US Patent:

20090246303, Oct 1, 2009
Filed:

Feb 11, 2009
Appl. No.:

12/369704
Inventors:

Andrei V. Gudkov - East Aurora NY, US
Vadim Krivokrysenko - Orchard Park NY, US
Lyudmila Burdelya - Lancaster NY, US
International Classification:

A61K 35/74
A61K 38/16
A61P 3/04
A61P 25/00
A61P 13/12
A61P 29/00
A61P 1/00
A61P 3/00
US Classification:

424780, 514 12
Abstract:

The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described.

Method Of Reducing The Effects Of Chemotherapy Using Flagellin Related Polypeptides
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US Patent:

20130324462, Dec 5, 2013
Filed:

Mar 26, 2013
Appl. No.:

13/850490
Inventors:

Andrei V. Gudkov - EAST AURORA NY, US
Vadim Krivokrysenko - Orchard Park NY, US
Lyudmila Burdelya - Lancaster NY, US
International Classification:

A61K 38/16
US Classification:

514 49, 514 11, 514 48, 514 183, 514 207, 514 177, 514 135, 514 164, 514 154
Abstract:

The use of flagellin and flagellin related polypeptides for reducing cancer treatment side effects in mammals is described.

Use Of Toll-Like Receptor Agonist For Treating Cancer
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US Patent:

20190275128, Sep 12, 2019
Filed:

Feb 19, 2019
Appl. No.:

16/279457
Inventors:

- Buffalo NY, US
Lyudmila BURDELYA - Lancaster NY, US
Andrei GUDKOV - East Aurora NY, US
International Classification:

A61K 39/00
A61K 38/16
C07K 14/255
A61K 39/395
C07K 16/28
C07K 14/195
Abstract:

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.

Use Of Toll-Like Receptor Agonist For Treating Cancer
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US Patent:

20180344823, Dec 6, 2018
Filed:

Jun 21, 2018
Appl. No.:

16/014419
Inventors:

- Buffalo NY, US
Lyudmila Burdelya - Lancaster NY, US
Andrei Gudkov - East Aurora NY, US
International Classification:

A61K 39/00
A61K 38/16
C07K 14/255
A61K 39/395
C07K 16/28
C07K 14/195
A61K 39/02
A61K 39/112
C07K 14/705
Abstract:

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.

Use Of Toll-Like Receptor Agonist For Treating Cancer
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US Patent:

20180028628, Feb 1, 2018
Filed:

Jun 23, 2017
Appl. No.:

15/631427
Inventors:

- Buffalo NY, US
Lyudmila Burdelya - Lancaster NY, US
Andrei Gudkov - East Aurora NY, US
International Classification:

A61K 39/00
C07K 14/255
C07K 16/28
C07K 14/195
A61K 38/16
A61K 39/395
C07K 14/705
A61K 39/02
A61K 39/112
Abstract:

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.

Use Of Toll-Like Receptor Agonist For Treating Cancer
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US Patent:

20170065692, Mar 9, 2017
Filed:

Aug 19, 2016
Appl. No.:

15/241757
Inventors:

- Buffalo NY, US
Lyudmila Burdelya - Lancaster NY, US
Andrei Gudkov - East Aurora NY, US
International Classification:

A61K 39/00
Abstract:

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.

Use Of Toll-Like Receptor Agonist For Treating Cancer
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US Patent:

20160206690, Jul 21, 2016
Filed:

Nov 23, 2015
Appl. No.:

14/949441
Inventors:

- Buffalo NY, US
Lyudmila Burdelya - Lancaster NY, US
Andrei Gudkov - East Aurora NY, US
International Classification:

A61K 38/16
A61K 39/395
A61K 39/00
Abstract:

The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present invention also relates to protecting the liver from a liver toxicity using a Toll-like receptor agonist.

Compositions And Methods Comprising Toll Like Receptor (Tlr) Stimulating Agents For Prophylaxis And Therapy For Damage To Dermal Epithelium
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US Patent:

20150328284, Nov 19, 2015
Filed:

Apr 2, 2013
Appl. No.:

14/389862
Inventors:

- Buffalo NY, US
Lyudmila BURDELYA - Lancaster NY, US
International Classification:

A61K 38/16
A61K 9/70
Abstract:

Provided are compositions and methods for prophylaxis and/or therapy of dermal damage. The compositions and methods involve Toll like receptor (TLR) agonists that can inhibit the formation or accelerate healing of dermal damage, and/or inhibit inflammation at near the location of the dermal damage. The TLR agonists can be TLR2 and/or TLR5 agonists. The compositions and methods are suitable for prophylaxis and/or therapy of dermal damage caused by radiation, or non-radiation thermal injury such as burns caused by contact with heated surfaces or heated objects, light, and for disruptions in integument resulting in cuts, such as incisions, or punctures. The compositions can be used topically, subcutaneously or systemically. Articles of manufacture coated or impregnated with TLR agonist(s) are also provided.

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Location:

Buffalo, NY

Industry:

Hospital & Health Care

Work:

Roswell Park Cancer Institute
Assistant Professor

Lyudmila G Burdelya