Lynda L Tremblay

US Patent:

7868002, Jan 11, 2011

Filed:

Sep 28, 2007

Appl. No.:

11/906056

Inventors:

Jane Daun - Dracut MA, US
Heather A. Davis - Haverhill MA, US
Bruce DeCosta - Salem NH, US
Fabian Gusovsky - Andover MA, US
Ieharu Hishinuma - Ibaraki, JP
Yimin Jiang - Londonderry NH, US
Toshihiko Kaneko - Ushiku, JP
Kouichi Kikuchi - Tsuchiura, JP
Seiichi Kobayashi - Belmont MA, US
André Lescarbeau - Somerville MA, US
Kenzo Muramoto - Tsukuba, JP
Norihito Ohi - Ibaraki, JP
Marc Pesant - Andover MA, US
Boris M. Seletsky - Andover MA, US
Motohiro Soejima - Tsukuba, JP
Mark Spyvee - Hampstead NH, US
Lynda Tremblay - Tewksbury MA, US
Ye Yao - North Andover MA, US
Hiromitsu Yokohama - Moriya, JP
Yan (Janet) Zhao - North Andover MA, US
Wanjun Zheng - Londonderry NH, US

Assignee:

Eisai R&D Management Co., Ltd. - Tokyo

International Classification:

C07D 413/14
C07D 471/02
A61K 31/4745
A61K 31/5377
A61P 11/06
A61P 19/02
A61P 25/00
A61P 3/10
A61P 9/00

US Classification:

5142342, 514303, 546118, 544405

Abstract:

As discussed above, there remains a need for the development of novel therapeutic agents useful for treating inflammatory or autoimmune and proliferative diseases. The present invention provides novel compounds of general formula (I),.

US Patent:

20050124649, Jun 9, 2005

Filed:

Jan 7, 2003

Appl. No.:

10/500840

Inventors:

Jane Daun - Dracut MA, US
Heather Davis - Haverhill MA, US
Bruce DeAcosta - Salem NH, US
Fabian Gusovsky - Andover MA, US
Ieharu Hishinuma - Moriya, JP
Yimin Jiang - Londonderry NH, US
Toshihiko Kaneko - Ushiku-shi, JP
Kouichi Kikuchi - Tsuchiura-shi, JP
Seiichi Kobayashi - Belmont MA, US
Andre Lescarbeau - Somerville MA, US
Kenzo Muramoto - Tsukuba-shi, JP
Norihito Ohi - Inashiki-gun, JP
Marc Pesant - Andover MA, US
Boris Seletsky - Andover MA, US
Mark Spyvee - Hampstead NH, US
Lynda Tremblay - Tewksbury MA, US
Ye Yao - North Andover MA, US
Hiromitsu Yokohama - Moriya-shi, JP
Yan (Janet) Zhao - North Andover MA, US
Wanjun Zheng - Londonderry NH, US

Assignee:

EISAI CO., LTD - Tokyo

International Classification:

C07D471/02
A61K031/4745

US Classification:

514303000, 546118000

Abstract:

The present invention provides compounds having formula (I), wherein R, R, Rand n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.

US Patent:

20110105427, May 5, 2011

Filed:

Nov 2, 2010

Appl. No.:

12/917669

Inventors:

Jane Daun - Dracut MA, US
Heather A. Davis - Haverhill MA, US
Bruce DeCosta - Salem NH, US
Fabian Gusovsky - Andover MA, US
Ieharu Hishinuma - Moriya, JP
Yimin Jiang - Londonderry NH, US
Toshihiko Kaneko - Ushiku-shi, JP
Kouichi Kikuchi - Tsuchiura-shi, JP
Seiichi Kobayashi - Belmont MA, US
André Lescarbeau - Somerville MA, US
Kenzo Muramoto - Tsukuba-shi, JP
Norihito Ohi - Inashiki-gun, JP
Marc Pesant - Andover MA, US
Boris M. Seletsky - Andover MA, US
Motohiro Soejima - Tsukuba-shi, JP
Mark Spyvee - Hampstead NH, US
Lynda Tremblay - Tewksbury MA, US
Ye Yao - North Andover MA, US
Hiromitsu Yokohama - Moriya-shi, JP
Yan (Janet) Zhao - North Andover MA, US
Wanjun Zheng - Londonderry NH, US

International Classification:

A61K 31/437
A61K 31/5377
A61K 31/496
A61K 31/541
A61K 31/4545
A61K 31/444
A61K 31/4709
A61K 31/55
A61K 31/439
A61K 31/4725
A61K 31/695
A61P 29/00
A61P 35/00
A61P 37/06
A61P 17/06
A61P 11/06
A61P 9/00

US Classification:

514 63, 514303, 5142342, 51425304, 5142285, 51421707, 514278, 51421021

Abstract:

The present invention provides compounds having formula (I):