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Lucienne Vera Ronco

age ~62

from Wellesley, MA

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Also known as:
  • Lucienne V Ronco
  • Lucienne Fam Ronco
  • Lucienne Ronco Ft
  • Lucienne V Rhind
Phone and address:
16 Garden Rd, Wellesley, MA 02481
Connected to:

Lucienne Ronco Phones & Addresses

  • 16 Garden Rd, Wellesley Hills, MA 02481
  • Wellesley, MA
  • Bangor, PA
  • 19 Burroughs St, Jamaica Plain, MA 02130
  • 19 Burroughs St APT 2, Jamaica Plain, MA 02130
  • Boston, MA
  • Northampton, PA
  • Los Angeles, CA

Work

  • Company:
    The broad institute
    May 2012
  • Address:
    320 Charles Street, Cambridge
  • Position:
    Director

Education

  • Degree:
    Ph.D
  • School / High School:
    University of California, Los Angeles
    1987 to 1993
  • Specialities:
    Biological Chemistry

Skills

Translational Research • Biotechnology • Program Management • Life Sciences • Pharmaceutical Industry • Molecular Biology • Biochemistry • Clinical Development • Drug Development • Cell Biology • Drug Discovery • Assay Development • Cell • Project Management • Management • Communication

Industries

Biotechnology

Us Patents

  • P38 Kinase Inhibitors Reduce Dux4 And Downstream Gene Expression For The Treatment Of Fshd

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  • US Patent:
    20200383963, Dec 10, 2020
  • Filed:
    Jan 21, 2020
  • Appl. No.:
    16/748217
  • Inventors:
    - Cambridge MA, US
    Luis Gustavo Alejandro ROJAS SOTO - Cambridge MA, US
    Owen Brendan WALLACE - Brookline MA, US
    Lucienne V. RONCO - Wellesley MA, US
    Ning SHEN - Cambridge MA, US
    Alan Scott ROBERTSON - Cambridge MA, US
    Aaron Nakwon CHANG - Lexington MA, US
  • International Classification:
    A61K 31/4418
    A61K 31/4439
    A61K 31/519
    A61K 31/437
    A61K 31/496
    A61K 31/5377
    A61K 31/53
    A61K 31/416
    A61K 31/454
    A61K 31/513
    A61K 31/506
    A61P 21/00
    C12Q 1/6883
    C12Q 1/6827
    C12Q 1/686
  • Abstract:
    The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDC1L, RFPL2, CCNA1, SLC34A2, TPRX1, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEF15, orZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.

  • Use Of P38 Inhibitors To Reduce Expression Of Dux4

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  • US Patent:
    20200332291, Oct 22, 2020
  • Filed:
    Oct 5, 2018
  • Appl. No.:
    16/753664
  • Inventors:
    - Cambridge MA, US
    Luis Gustavo Alejandro ROJAS SOTO - Cambridge MA, US
    Owen Brendan WALLACE - Brookline MA, US
    Lucienne V. RONCO - Wellesley MA, US
    Ning SHEN - Cambridge MA, US
    Alan Scott ROBERTSON - Cambridge MA, US
    Aaron Nakwon CHANG - Lexington MA, US
  • International Classification:
    C12N 15/113
    A61K 31/4418
    A61K 31/4439
    A61K 31/519
    A61K 31/506
    A61P 21/00
  • Abstract:
    The present invention relates to compositions and methods of inhibiting p38 kinase to reduce gene and protein expression of DUX4 and downstream genes regulated by DUX4. The present invention further relates to methods for treating patients suffering from diseases associated with increased expression of DUX4 or expression of an aberrant form of DUX4, such as Facioscapulohumeral muscular dystrophy (FSHD).

Resumes

Lucienne Ronco Photo 1

Vice President Translational Medicine

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Location:
16 Garden Rd, Wellesley, MA 02481
Industry:
Biotechnology
Work:
The Broad Institute - 320 Charles Street, Cambridge since May 2012
Director
Catabasis Pharmaceuticals, Inc. - Cambridge, MA Apr 2011 - Jun 2012
Vice President Research
AstraZeneca R&D May 2001 - Mar 2011
Director
Pfizer May 1999 - May 2001
Scientist
Education:
University of California, Los Angeles 1987 - 1993
Ph.D, Biological Chemistry Tufts University 1980 - 1984
BS, Biology and Environmental Sciences
Skills:
Translational Research
Biotechnology
Program Management
Life Sciences
Pharmaceutical Industry
Molecular Biology
Biochemistry
Clinical Development
Drug Development
Cell Biology
Drug Discovery
Assay Development
Cell
Project Management
Management
Communication
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