Lowell David Waterbury from San Carlos, CA, age 83

Furan Nitrone Compounds
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US Patent:

6376540, Apr 23, 2002
Filed:

Dec 17, 1999
Appl. No.:

09/230065
Inventors:

Judith A. Kelleher - Fremont CA
Kirk R. Maples - San Jose CA
Lowell David Waterbury - San Carlos CA
Allan L. Wilcox - Mountain View CA
Hong Xu - Cupertino CA
Yong-Kang Zhang - Santa Clara CA
Assignee:

Centaur Pharmaceuticals, Inc. - Sunnyvale CA
International Classification:

A61K 3134
US Classification:

514471, 5142315, 5142541
Abstract:

Disclosed are furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compounds are useful as analytical reagents for detecting free radicals and as therapeutics for treating a wide variety of medical dysfunctions and diseases.

Methods For Treating Medical Dysfunctions And Diseases Using Furan Nitrone Compounds
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US Patent:

60515716, Apr 18, 2000
Filed:

May 24, 1999
Appl. No.:

9/317266
Inventors:

Judith A. Kelleher - Fremont CA
Kirk R. Maples - San Jose CA
Lowell David Waterbury - San Carlos CA
Hong Xu - Cupertino CA
Yong-Kang Zhang - Santa Clara CA
Assignee:

Centaur Pharmaceuticals, Inc. - Sunnyvale CA
International Classification:

A61K 3134
US Classification:

5142315
Abstract:

Disclosed are methods for treating a patient with an acute central nervous system or cardiovascular disorder or a neurodegenerative, autoimmune or inflammatory disease using a pharmaceutical composition containing a pharmaceutically acceptable carrier and an effective amount of a furan nitrone compound.

Inhibition Of Angiogenesis
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US Patent:

62553534, Jul 3, 2001
Filed:

Mar 12, 1999
Appl. No.:

9/267510
Inventors:

Lowell D. Waterbury - San Carlos CA
Kenneth W. Narducy - San Jose CA
Allan L. Wilcox - Mountain View CA
Assignee:

Centaur Pharmaceuticals, Inc. - Sunnyvale CA
International Classification:

A61K 31255
US Classification:

514643
Abstract:

Certain simple chemical agents, referred to herein as nitrone related therapeutics or "NRTs", when administered to a patient susceptible to neovascularization (angiogenesis), can intervene and inhibit the disease's progress. Methods for therapeutically and prophylactically inhibiting angiogenesis by administering one or more NRTs are disclosed as are pharmaceutical compositions for use in such methods of treating. NRTs useful in these compositions and therapeutic methods are also disclosed.

Furan Nitrone Compounds
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US Patent:

59425075, Aug 24, 1999
Filed:

Jul 17, 1997
Appl. No.:

8/895968
Inventors:

Judith A. Kelleher - Fremont CA
Kirk R. Maples - San Jose CA
Lowell David Waterbury - San Carlos CA
Allan L. Wilcox - Mountain View CA
Hong Xu - Cupertino CA
Yong-Kang Zhang - Santa Clara CA
Assignee:

Centaur Pharmaceuticals, Inc. - Sunnyvale CA
International Classification:

C07D30752
C07D40512
C07D41312
A61K 3134
US Classification:

5142315
Abstract:

Disclosed are furan nitrone compounds and pharmaceutical compositions containing such compounds. The disclosed compounds are useful as analytical reagents for detecting free radicals and as therapeutics for treating a wide variety of medical dysfunctions and diseases.