Lbachir B Benmohamed

US Patent:

20060280752, Dec 14, 2006

Filed:

Jan 19, 2005

Appl. No.:

11/039578

Inventors:

Lbachir BenMohamed - Arcadia CA, US
Anthony Nesburn - Malibu CA, US

International Classification:

A61K 39/245
G06F 19/00

US Classification:

424186100, 424231100, 702020000

Abstract:

Described herein are peptide epitopes effective in the treatment of herpes simplex virus (HSV), as well as vaccines and other therapeutic compositions including the same. In various embodiments, the compositions of the present invention may include a pharmaceutically acceptable adjuvant to enhance the delivery and/or pharmacological efficacy of the epitope. Also described are methods for treating and preventing HSV with the aforementioned epitopes, such as by administering a vaccine including the same. Other methods describe the use of the TEPITOPE algorithm to identify epitopes that may be useful in the treatment of HSV and related or unrelated disease conditions.

US Patent:

20080299140, Dec 4, 2008

Filed:

May 23, 2003

Appl. No.:

10/516035

Inventors:

Bertrand Georges - Bauvin, FR
Helene Gras-Masse - Merignies, FR
Lbachir BenMohamed - Mission Viejo CA, US
Anthony B. Nesburn - Mailbu CA, US

Assignee:

The Regents of the University of California, - Oakland CA

International Classification:

A61K 39/245
A61P 31/12

US Classification:

4241861, 4242311

Abstract:

Immunogenic composition comprising at least one Herpes Simplex Virus type 1 (HSV-1) and/or type 2 (HSV-2) peptide sequence hearing at least one epitope from glycoprotein D (gD) and/or glycoprotein B (gB), a pharmaceutical carrier and/or a human compatible adjuvant, peptide sequences and uses thereof for prevention or treatment of an HSV condition.

US Patent:

20030219448, Nov 27, 2003

Filed:

Aug 6, 2002

Appl. No.:

10/213053

Inventors:

Lbachir BenMohamed - Arcadia CA, US
Anthony Nesburn - Malibu CA, US

Assignee:

CEDARS-SINAI MEDICAL CENTER

International Classification:

A01N037/18
A61K038/00
A61K039/12
A61K039/245
A61K039/255
A61K039/265
A61K039/27

US Classification:

424/186100, 424/229100, 514/002000

Abstract:

Described herein are peptide epitopes effective in the treatment of herpes simplex virus (HSV), as well as vaccines and other therapeutic compositions including the same. In various embodiments, the compositions of the present invention may include a pharmaceutically acceptable adjuvant to enhance the delivery and/or pharmacological efficacy of the epitope. Also described are methods for treating and preventing HSV with the aforementioned epitopes, such as by administering a vaccine including the same. Other methods describe the use of the TEPITOPE algorithm to identify epitopes that may be useful in the treatment of HSV and related or unrelated disease conditions.

US Patent:

20200046827, Feb 13, 2020

Filed:

Aug 8, 2019

Appl. No.:

16/535534

Inventors:

- OAKLAND CA, US
Lbachir BenMohamed - Irvine CA, US

International Classification:

A61K 39/245
A61P 31/22
C12N 7/00

Abstract:

The present invention relates to compositions comprising HSV antigens and methods for their use in the treatment or prevention of asymptomatic and symptomatic herpesvirus infection, or recurrence.