Lbachir BenMohamed - Arcadia CA, US Anthony Nesburn - Malibu CA, US
International Classification:
A61K 39/245 G06F 19/00
US Classification:
424186100, 424231100, 702020000
Abstract:
Described herein are peptide epitopes effective in the treatment of herpes simplex virus (HSV), as well as vaccines and other therapeutic compositions including the same. In various embodiments, the compositions of the present invention may include a pharmaceutically acceptable adjuvant to enhance the delivery and/or pharmacological efficacy of the epitope. Also described are methods for treating and preventing HSV with the aforementioned epitopes, such as by administering a vaccine including the same. Other methods describe the use of the TEPITOPE algorithm to identify epitopes that may be useful in the treatment of HSV and related or unrelated disease conditions.
Immunogenic Composition And Peptide Sequences For Prevention And Treatment Of An Hsv Condition
Bertrand Georges - Bauvin, FR Helene Gras-Masse - Merignies, FR Lbachir BenMohamed - Mission Viejo CA, US Anthony B. Nesburn - Mailbu CA, US
Assignee:
The Regents of the University of California, - Oakland CA
International Classification:
A61K 39/245 A61P 31/12
US Classification:
4241861, 4242311
Abstract:
Immunogenic composition comprising at least one Herpes Simplex Virus type 1 (HSV-1) and/or type 2 (HSV-2) peptide sequence hearing at least one epitope from glycoprotein D (gD) and/or glycoprotein B (gB), a pharmaceutical carrier and/or a human compatible adjuvant, peptide sequences and uses thereof for prevention or treatment of an HSV condition.
Peptide Epitope-Based Vaccine For Treating Herpes Simplex Virus Infections And Related Diseases
Described herein are peptide epitopes effective in the treatment of herpes simplex virus (HSV), as well as vaccines and other therapeutic compositions including the same. In various embodiments, the compositions of the present invention may include a pharmaceutically acceptable adjuvant to enhance the delivery and/or pharmacological efficacy of the epitope. Also described are methods for treating and preventing HSV with the aforementioned epitopes, such as by administering a vaccine including the same. Other methods describe the use of the TEPITOPE algorithm to identify epitopes that may be useful in the treatment of HSV and related or unrelated disease conditions.
Protection Against Recurrent Genital Herpes By Therapeutic Immunization With Herpes Simplex Virus Type 2 Ribonucleotide Reductase Protein Subunits
- OAKLAND CA, US Lbachir BenMohamed - Irvine CA, US
International Classification:
A61K 39/245 A61P 31/22 C12N 7/00
Abstract:
The present invention relates to compositions comprising HSV antigens and methods for their use in the treatment or prevention of asymptomatic and symptomatic herpesvirus infection, or recurrence.
Name / Title
Company / Classification
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Lbachir Benmohamed
Micro Antigen Technologies, LLC Technology Development · Business Services