Yehoshua Shachar - Santa Monica CA, US Leslie Farkas - Ojai CA, US Bruce Marx - Ojai CA, US David Johnson - West Hollywood CA, US Laszlo Farkas - Ojai CA, US Thomas C. Chen - La Canada CA, US
Assignee:
Pharmaco-Kinesis Corporation - Inglewood CA
International Classification:
A61M 31/00
US Classification:
604508, 604506, 604507, 604509, 6048901
Abstract:
A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
Magnetic Breather Pump And A Method For Treating A Brain Tumor Using The Same
Yehoshua Shachar - Santa Monica CA, US Thomas C. Chen - La Canada CA, US Leslie Farkas - Ojai CA, US Bruce Marx - Ojai CA, US David Johnson - West Hollywood CA, US Laszlo Farkas - Ojai CA, US
Assignee:
Pharmaco-Kinesis Corporation - Inglewood CA
International Classification:
A61K 9/22
US Classification:
6048911, 6048901, 604 65, 604 66, 604 67, 604508
Abstract:
A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
Apparatus For Magnetically Deployable Catheter With Mosfet Sensor And Method For Mapping And Ablation
Yehoshua Shachar - Santa Monica CA, US Laszlo Farkas - Ojai CA, US Eli Gang - Beverly Hills CA, US
Assignee:
Magnetecs, Inc. - Inglewood CA
International Classification:
A61B 5/04
US Classification:
600374
Abstract:
A mapping and ablation catheter is described. In one embodiment, the catheter includes a MOSFET sensor array that provides better fidelity of the signal measurements as well as data collection and reduces the error generated by spatial distribution of the isotropic and anisotropic wavefronts. In one embodiment, the system maps the change in potential in the vicinity of an activation wavefront. In one embodiment, the mapping system tracks the spread of excitation in the heart, with properties such as propagation velocity changes. In one embodiment, during measurement, the manifold carrying the sensor array expands from a closed position state to a deployable open state. Spatial variation of the electrical potential is captured by the system's ability to occupy the same three-dimensional coordinate set for repeated measurements of the desired site. In one embodiment, an interpolation algorithm tracks the electrogram data points to produce a map relative to the electrocardiogram data.
High Power Wireless Resonant Energy Transfer System
Josh Shachar - Santa Monica CA, US Thomas Chen - La Canada CA, US Leslie Farkas - Ojai CA, US Winston Wu - Alhambra CA, US Kyle Zimmerman - Los Angeles CA, US Moran Cerf - Los Angeles CA, US Bruce Marx - Ojai CA, US David Johnson - West Hollywood CA, US Laszlo Farkas - Ojai CA, US
Assignee:
Pharmaco-Kinesis Corporation - Inglewood CA
International Classification:
A61B 1/32
US Classification:
600202, 600544
Abstract:
Described is a surgical system for monitoring a patient's condition during surgery. One aspect is a non-contact EEG sensor. The non-contact EEG sensor can be used to predict the onset of physiological disorders. Another aspect includes the use of a plurality of pressure sensors to determine the pressure applied by retractors on the patient, including the brain and other organs.
Metronomic Convection Enhanced Delivery Of Intrathecal Chemotherapy Using An Implanted Magnetic Breather Pump (Mbp) For Leptomeningeal Carcinomatosis
Yehoshua Shachar - Santa Monica CA, US Thomas C. Chen - La Canada CA, US Leslie Farkas - Ojai CA, US Bruce Marx - Ojai CA, US David Johnson - West Hollywood CA, US Laszlo Farkas - Ojai CA, US
Assignee:
Pharmaco-Kinesis Corporation - Inglewood CA
International Classification:
A61K 9/22
US Classification:
6048911
Abstract:
A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
Enhanced Method For Delivering Bevacizumab (Avastin) Into A Brain Tumor Using An Implanted Magnetic Breather Pump
Yehoshua Shachar - Santa Monica CA, US Thomas C. Chen - La Canada CA, US Leslie Farkas - Ojai CA, US Bruce Marx - Ojai CA, US David Johnson - West Hollywood CA, US Laszlo Farkas - Ojai CA, US
Assignee:
Pharmaco-Kinesis Corporation - Inglewood CA
International Classification:
A61K 9/22
US Classification:
6048911
Abstract:
A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents mixed with Avastin at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, the medicating agent Avastin is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. In cases where a tumor resection is not performed, an intratumoral catheter will be implanted. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.
System And Method For A Catheter Impedance Seeking Device
Yehoshua Shachar - Santa Monica CA, US Bruce Marx - Ojai CA, US Leslie Farkas - Ojai CA, US Laszlo Farkas - Ojai CA, US David Johnson - West Hollywood CA, US Eli Gang - Los Angeles CA, US
Assignee:
Magnetecs, Inc. - Inglewood CA
International Classification:
A61B 5/05 A61B 17/00
US Classification:
600424
Abstract:
A tissue-contact seeking method and apparatus is described that enhances catheter position detection and control systems in making and maintaining continuous tissue contact in a highly dynamic frame, such as under the rigors of cardiac motion. Tissue-seeking logical routines use a tissue contact sensing system to advance a catheter to relatively continuous tissue contact, or detect obstacles, in cooperation with the catheter position detection and control systems. Additional logical routines are capable of optimizing the contact direction of the catheter tip by controlling the rotation angle and chamber position of the introducer.