Larry Yun Fang

US Patent:

20050153976, Jul 14, 2005

Filed:

Dec 16, 2004

Appl. No.:

11/013676

Inventors:

Larry Fang - Plainsboro NJ, US
Prudence Bradley - Cranford NJ, US
Ping Lee - Toronto, CA

International Classification:

A61K031/496

US Classification:

514253110

Abstract:

Disclosed herein are novel compositions useful for the treatment of androgen dependant diseases.

US Patent:

20090111831, Apr 30, 2009

Filed:

Dec 9, 2008

Appl. No.:

12/331015

Inventors:

Larry Yun Fang - Plainsboro NJ, US
Prudence K. Bradley - Cranford NJ, US
Ping L. Lee - Radnor NJ, US

International Classification:

A61K 31/496
A61P 5/26

US Classification:

51425313

Abstract:

Disclosed herein are novel compositions useful for the treatment of androgen dependant diseases.

US Patent:

20110034478, Feb 10, 2011

Filed:

Apr 15, 2009

Appl. No.:

12/937881

Inventors:

Larry Yun Fang - Plainsboro NJ, US
Jiansheng Wan - Warren NJ, US
David Harris - New Providence NJ, US

International Classification:

A61K 31/496
A61P 31/10

US Classification:

51425407

Abstract:

The present invention provides a solid molecularly dispersed composition comprising a poorly water soluble and weakly basic azole antifungal compound and a pH sensitive polymer, pharmaceutical compositions, comprising the solid molecularly dispersed composition of the invention and methods of treating and/or preventing a fungal infection in a patient in need thereof comprising orally administering a pharmaceutical composition comprising a composition of the invention to a patient in need thereof. Preferably the antifungal, compound is posaconazole, and the pH sensitive polymer is HPMCAS.

US Patent:

20110123627, May 26, 2011

Filed:

Apr 15, 2009

Appl. No.:

12/999547

Inventors:

Larry Yun Fang - Plainsboro NJ, US
David Harris - New Providence NJ, US
Gopal Krishna - North Brunswick NJ, US
Russell C. Prestipino - Hoboken NJ, US
Marc Steinman - Livingston NJ, US
Jiansheng Wan - Warren NJ, US
Hetty Anne Waskin - Skillman NJ, US

International Classification:

A61K 31/496
A61K 9/14
A61P 31/10

US Classification:

424489, 51425407

Abstract:

The present application provides novel compositions comprising posaconazole and a polymer wherein the composition has a glass transition temperature (Tg) of less than about 1100 C. The application also describes compositions comprising posaconazole and a polymer having a bulk density of greater than about 0.4 mg/mL. The application also describes compositions comprising posaconazole and a polymer which provide an exposure (AUCtf) of at least about 10,000 nghr/mL when administered to a patient in a fasted state. The application also describes a novel process for preparing these compositions. The preff erred polymer is HPMCAS. Preferably the composition is an extruded material.