Eric Chellquist - Plymouth Meeting PA, US Mary Doubleday - Plymouth Meeting PA, US Charles Gilbert - Plymouth Meeting PA, US Xuehai Zhang - Plymouth Meeting PA, US Michael McLane - Plymouth Meeting PA, US Kyle Armbruster - Plymouth Meeting PA, US Roy Levitt - Plymouth Meeting PA, US
International Classification:
A61K 31/56 C07J 41/00
US Classification:
514178000, 552515000
Abstract:
The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation.
Polymorphic And Amorphous Salt Forms Of Squalamine Dilactate
Eric Chellquist - Plymouth Meeting PA, US Mary Doubleday - Plymouth Meeting PA, US Charles Gilbert - Plymouth Meeting PA, US Xuehai Zhang - Plymouth Meeting PA, US Michael McLane - Plymouth Meeting PA, US Kyle Armbruster - Plymouth Meeting PA, US Roy C. Levitt - Plymouth Meeting PA, US
The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation.