Keyue Shen

age ~46

from South Pasadena, CA

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Also known as:

Connected to:

Micropatterned T Cell Stimulation
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US Patent:

20080317724, Dec 25, 2008
Filed:

Jan 18, 2008
Appl. No.:

12/009633
Inventors:

Lance Kam - New York NY, US
Keyue Shen - New York NY, US
Michael L. Dustin - New York NY, US
Vedra Kaye Thomas - New York NY, US
International Classification:

A61K 35/12
C12M 1/00
A61P 31/00
C12N 5/06
US Classification:

424 9371, 4352831, 4353723
Abstract:

The invention relates to methods of expanding, stimulating or activating T cells by modulating the spatial organization of signal molecules presented to the T cells.

Activation And Expansion Of T Cell Subsets Using Biocompatible Solid Substrates With Tunable Rigidity
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US Patent:

20150030619, Jan 29, 2015
Filed:

Sep 6, 2012
Appl. No.:

14/342599
Inventors:

- New York NY, US
- Philadelphia PA, US
Keyue Shen - Cambridge MA, US
Hueli Hao - Cleveland OH, US
Roderick O'Connor - Philadelphia PA, US
Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY
International Classification:

A61K 35/14
C12N 5/0783
US Classification:

4241841, 435375
Abstract:

The present invention provides compositions and methods for activation and expansion of T cells using a biocompatible solid substrate with tunable rigidity. Rigidity of a substrate is an important parameter that can be used to control the overall expansion and differentiation of T cells.

Keyue Shen Phones & Addresses