Kevin J Horan

US Patent:

8496800, Jul 30, 2013

Filed:

Aug 14, 2009

Appl. No.:

13/059671

Inventors:

Wei Zhang - Norwood MA, US
Kevin Horan - Raynham MA, US
Laura S. Uretsky - Milford MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 27/333

US Classification:

2057895, 204416, 204418

Abstract:

Methods are disclosed for reducing the shift in EMF bias in a magnesium ion selective electrode, comprising the step of: contacting the electrode with a composition comprising a polyoxyalkylene nonionic surfactant; wherein the polyoxyalkylene nonionic surfactant has an HLB greater than about 18. Additional aspects of the present invention are directed to methods, comprising the steps of: contacting a magnesium ion selective electrode with a composition comprising a polyoxyalkylene nonionic surfactant, wherein the polyoxyalkylene nonionic surfactant has an HLB greater than about 18; and measuring a biologically relevant level of a blood electrolyte in a blood composition with the electrode. In certain embodiments, the polyoxyalkylene nonionic surfactant is polyoxy ethylene (100) stearyl ether and the blood electrolyte is magnesium ion.

US Patent:

20220256849, Aug 18, 2022

Filed:

Jul 20, 2020

Appl. No.:

17/597866

Inventors:

- Tarrytown NY, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

A01N 43/66

Abstract:

Composition(s), device(s), kit(s), and method(s) for improved biocide formulations that remove contaminants (and the effects related thereto) from at least one analyte detection sensor, while simultaneously preserving and/or extending the functional life of the at least one analyte detection sensor.

US Patent:

20230104001, Apr 6, 2023

Filed:

Dec 2, 2022

Appl. No.:

18/061128

Inventors:

- Tarrytown NY, US
Brian Holman - Medfield MA, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 27/333
G01N 33/84
C12Q 1/25
G01N 27/416
G01N 33/50
G01N 33/49
G01N 27/30

Abstract:

A fluid analyzer for analyzing fluid samples comprising one or more analytes and a method of calibrating such. The fluid analyzer includes a control system to control at least one automated valve to pass at least three calibration reagents through a fluid channel to a secondary ion selective electrode, a primary ion selective electrode, and a reference electrode, and determine calibration information using calibration logic from signals generated by a meter, control the at least one automated valve to selectively pass different subsets of the at least three calibration reagents through the fluid channel to the secondary ion selective electrode, the primary ion selective electrode, and the reference electrode, and determine re-calibration information using the signals generated by the meter and at least one of the calibration information and re-calibration logic.

US Patent:

20210405024, Dec 30, 2021

Filed:

Dec 19, 2018

Appl. No.:

16/769395

Inventors:

- Tarrytown NY, US
Kevin Horan - Raynham MA, US
Murli Narayan - Norfolk MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 33/49
A61K 47/18
A61K 47/26
G01N 27/327

Abstract:

Disclosed herein are compositions comprising oxygen, a sugar or sugar alcohol, and an amino acid, wherein the amino acid is present in an amount sufficient to stabilize the oxygen. Also provided are aqueous diagnostic quality controls or calibration reagents and methods of stabilizing oxygen in a liquid solution.

US Patent:

20210132092, May 6, 2021

Filed:

Jan 15, 2021

Appl. No.:

17/150113

Inventors:

- Tarrytown NY, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 33/96
G01N 33/84
A61K 38/00
C12Q 1/58

Abstract:

Aqueous calibration or quality control reagents that include urea are disclosed; the reagents may further include at least one amino acid-containing composition to provide pH stability thereto. Methods of production and use thereof are also disclosed.

US Patent:

20200340939, Oct 29, 2020

Filed:

Jul 9, 2020

Appl. No.:

16/924898

Inventors:

- Tarrytown NY, US
Brian Holman - Medfield MA, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 27/333
G01N 33/84
C12Q 1/25
G01N 27/416
G01N 33/50
G01N 33/49
G01N 27/30

Abstract:

A fluid analyzer for analyzing fluid samples comprising one or more analytes and a method of calibrating such. The fluid analyzer includes a control system to control at least one automated valve to pass at least three calibration reagents through a fluid channel to a secondary ion selective electrode, a primary ion selective electrode, and a reference electrode, and determine calibration information using calibration logic from signals generated by a meter, control the at least one automated valve to selectively pass different subsets of the at least three calibration reagents through the fluid channel to the secondary ion selective electrode, the primary ion selective electrode, and the reference electrode, and determine re-calibration information using the signals generated by the meter and at least one of the calibration information and re-calibration logic.

US Patent:

20200173955, Jun 4, 2020

Filed:

Feb 5, 2020

Appl. No.:

16/782511

Inventors:

- Tarrytown NY, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 27/333
G01N 33/487
G01N 27/416

Abstract:

A magnesium sensing membrane is disclosed for use in a potentiometric ion selective electrode that exhibits improved stability upon exposure to surfactant-containing reagents. Kits containing same are disclosed, along with methods of production and use of the magnesium sensing membrane.

US Patent:

20190204261, Jul 4, 2019

Filed:

Mar 11, 2019

Appl. No.:

16/297811

Inventors:

- Tarrytown NY, US
Kevin Horan - Raynham MA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

G01N 27/333
G01N 27/416

Abstract:

A magnesium sensing membrane is disclosed for use in a potentiometric ion selective electrode that exhibits improved stability upon exposure to surfactant-containing reagents. Kits containing same are disclosed, along with methods of production and use of the magnesium sensing membrane.