Kenneth James Ingold

US Patent:

7595880, Sep 29, 2009

Filed:

Nov 8, 2006

Appl. No.:

11/595168

Inventors:

Gerald A. Long - Greensboro NC, US
Kenneth A. Ingold - Greensboro NC, US
A. Leonard Rhyne - Winston-Salem NC, US

Assignee:

Lorillard Licensing Company, LLC - Greensboro NC

International Classification:

G01N 21/84

US Classification:

356429, 356431

Abstract:

A method and system for capturing and analyzing an image of a moving web of cigarette paper having a plurality of transverse banded regions. The captured images of the moving web of cigarette paper are analyzed to determine various characteristics of a population of cigarettes made with the cigarette paper. Each captured image is decomposed into a matrix of grey scale values associated with individual pixels of the image. The values are further processed to determine a width of a banded region on the cigarette paper. The average widths of banded regions, as well as the standard deviation of widths may be analyzed and correlated to freeburn and ignition propensity characteristics of a population of cigarettes formed from the measured cigarette paper.

US Patent:

20050159598, Jul 21, 2005

Filed:

Feb 25, 2003

Appl. No.:

10/505337

Inventors:

Kenneth Ingold - Research Triangle Park NC, US
Bing Liu - Durham NC, US

International Classification:

C07D417/02
C07D413/02
C07F001/02
C07F007/04

US Classification:

540603000, 548200000, 548215000, 546209000, 26066500R, 556427000

Abstract:

The present invention relates to a process for the preparation of certain chemical compounds. In particular, the present invention relates to a method for the preparation of compounds that have been shown to activate human peroxisome proliferator activated receptors (“hPPARs”). The present invention also relates to certain chemical compounds useful as intermediates in the preparation of hPPAR active compounds.

US Patent:

20110230555, Sep 22, 2011

Filed:

Jun 24, 2009

Appl. No.:

12/999732

Inventors:

David Middlemiss - Hertfordshire, GB
Kenneth J. Ingold - Durham NC, US

International Classification:

A61K 31/216
C07C 229/26
C12N 9/99
A61P 3/10
A61P 3/04
A61P 9/04
A61P 9/10
A61P 9/12
A61P 3/06
A61P 5/50
A61P 17/00
A61P 17/06
A61P 35/00
A61K 31/22

US Classification:

514542, 560 34, 435184, 560169, 514551

Abstract:

The present invention provides compounds and methods for the treatment of diseases or disorders such as heart failure, hyperlipidemia, hypercholesterolemia, gonadotropin deficiency, diabetes mellitus, metabolic syndrome, hyperglycemia, insulin resistance, glucose intolerance, obesity, psoriasis, atopic dermatitis, and cancer.

US Patent:

20110237536, Sep 29, 2011

Filed:

Oct 9, 2009

Appl. No.:

13/122771

Inventors:

John R. Didsbury - Raleigh NC, US
Kenneth J. Ingold - Durham NC, US
Linda Goff Jet - Hillsborough NC, US
Andrew Xian Chen - San Diego CA, US
Hailiang Chen - San Diego CA, US

International Classification:

A61K 31/7076
A61P 29/00
A61P 25/04
B82Y 5/00

US Classification:

514 45, 977773, 977915

Abstract:

The present invention relates to the use of spicamycin derivatives for treatment and/or prevention of pain, including neuropathic pain. The invention further relates to pharmaceutical compositions of spicamycin derivatives suitable for treatment or prevention of pain.

US Patent:

61472549, Nov 14, 2000

Filed:

Aug 6, 1999

Appl. No.:

9/319496

Inventors:

Barry Riddle Sickles - Durham NC
Kenneth James Ingold - Durham NC
Christopher John Wallis - Stevenage, GB

Assignee:

Glaxo Wellcome Inc. - Research Triangle Park NC

International Classification:

C07B 5700

US Classification:

562402

Abstract:

A process for the preparation of carbocyclic stereoisomers of formulae (I), (I'), (IIA'), (IIB'), (VA') and (VB'), including enantiomerically pure (IIA'), (I) and (I') utilizing fractional crystallization of salts formed with a chiral base; a reducing agent; a protecting group removing agent or a protecting group providing agent.