Kenichi Yamane from Gaithersburg, MD, age 54

Protein Demethylases Comprising A Jmjc Domain
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US Patent:

20090203057, Aug 13, 2009
Filed:

Oct 27, 2006
Appl. No.:

12/091205
Inventors:

Yi Zhang - Chapel Hill NC, US
Yuichi Tsukada - Fukuoka, JP
Kenichi Yamane - Gaithersburg MD, US
Robert John Klose - Oxford, GB
International Classification:

C12Q 1/34
US Classification:

435 18
Abstract:

Post-translational modification, including protein methylation, plays an important role in regulating protein function. The present invention provides a novel assay for evaluating demethylase activity and the discovery of a family of protein demethylases comprising a novel demethylase motif.

Protein Demethylases Comprising A Jmjc Domain
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US Patent:

20160244802, Aug 25, 2016
Filed:

Feb 25, 2016
Appl. No.:

15/053920
Inventors:

- Chapel Hill NC, US
Yuichi Tsukada - Fukuoka-shi, JP
Kenichi Yamane - Gaithersburg MD, US
Robert John Klose - Oxford, GB
International Classification:

C12Q 1/26
G01N 33/68
Abstract:

Post-translational modification, including protein methylation, plays an important role in regulating protein function. The present invention provides a novel assay for evaluating demethylase activity and the discovery of a family of protein demethylases comprising a novel demethylase motif.