The University of Texas Health Science Center at Houston May 2012 - Sep 2015
Instructor
The University of Texas Health Science Center at Houston May 2012 - Sep 2015
Assistant Professor
The University of Texas Health Science Center at Houston May 2010 - May 2012
Postdoctoral Research Fellow
University of Health Science Center Houston Apr 2008 - May 2010
Postdoctoral Research Fellow
Education:
The University of Texas Health Science Center at Houston (Uthealth) 2004 - 2008
Doctorates, Doctor of Philosophy, Molecular Biology, Pharmacology
Clarkson University 2002 - 2004
Master of Science, Masters, Biochemistry
Clarkson University 1998 - 2002
Bachelors, Bachelor of Science, Chemical Engineering
Thousand Islands High School 1998
Qingyun Lin - The Woodlands TX, US Kendra Carmon - Houston TX, US Xing Gong - Pearland TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
C12Q 1/66
US Classification:
435 618, 5303871
Abstract:
A composition and method for detecting the ability of a compound to modulate the activity of LGR4, LGR5, or LGR6 receptors in a cell. LGR4, LGR5, and LGR6 are capable of activating the Wnt/β-catenin signaling system which plays essential roles in embryonic development and in the self-renewal and maintenance of adult stem cells.
Mutants And Drug Conjugates Of R-Spondins And Use Thereof
Recombinant R-spondin (RSPO) polypeptides are provided, such as RSPO that is fused with Fc and/or comprises a conjugated therapeutic agent. Methods for using such polypeptides, for example in treating cancer are also provided.
Lgr4 Specific Monoclonal Antibodies And Methods Of Their Use
- Austin TX, US Xing GONG - Houston TX, US Kendra CARMON - Houston TX, US
International Classification:
A61K 47/68 A61P 35/00 A61K 39/395
Abstract:
Isolated or recombinant anti-LGR4 monoclonal antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer.