Kazys A Razgaitis

US Patent:

50029410, Mar 26, 1991

Filed:

Oct 11, 1988

Appl. No.:

7/255816

Inventors:

Jerry L. Adams - Wayne PA
Paul E. Bender - Cherry Hill NJ
John G. Gleason - Downington PA
Nabil Hanna - Berwyn PA
John F. Newton - West Chester PA
Carl D. Perchonock - Bethesda MD
Kazys Razgaitis - Rosemont PA

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 3132
A61K 31415
C07D40104
C07F 502

US Classification:

514186

Abstract:

Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway inhibitors.

US Patent:

51341506, Jul 28, 1992

Filed:

Dec 4, 1989

Appl. No.:

7/445581

Inventors:

Paul E. Bender - Cherry Hill NJ
John G. Gleason - Delran NJ
Don E. Griswold - North Wales PA
Nabil Hanna - Berwyn PA
Ivan Lantos - Blackwood NJ
Kazys A. Razgaitis - Rosemont PA
Henry M. Sarau - Hatfield PA
Susan C. Shilcrat - Bala Cynwyd PA

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

A61K 3144
A61K 31445
A61K 31415
A61K 31425

US Classification:

514318

Abstract:

A method of inhibiting the 5-lipoxygenase pathway in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a diaryl- substituted imidazole fused to a thiazole pyrrolidine, thiazide or piperidine ring to such animal.