Brett T. Watson - Verloese, DK Katherine S. Takaki - Middletown CT Joseph P. Yevich - Southington CT James R. Epperson - Cromwell CT George N. Karageorge - Meriden CT Karen L. Leboulluec - Durham CT
Assignee:
Bristol-Myers Squibb Company - Princteon NJ
International Classification:
A61K 3116 C07C23305
US Classification:
514630
Abstract:
Novel substituted fluorene compunds of Formula I are active as melatonergic agents: ##STR1## wherein: X=H, halogen, OH or OZ; Z=C. sub. 1-6 alkyl; --(CH. sub. 2). sub. m --CF. sub. 3 (m=0-2); CD. sub. 3 ; or ##STR2## n=1 or 2; and R=C. sub. 1-6 alkyl, C. sub. 3-6 cycloalkyl, C. sub. 2-4 alkenyl, halogen substituted C. sub. 1-6 alkyl, or C. sub. 1-6 alkoxy substituted C. sub. 1-6 alkyl.
Graham S. Poindexter - Old Saybrook CT Marc Bruce - Wallingford CT Graham Johnson - Madison CT Karen LeBoulluec - Wallingford CT Jeffrey W. Noonan - Branford CT
Assignee:
Bristol-Myers Squibb Company - New York NY
International Classification:
A61K 3116 A61K 3117 C07D40110
US Classification:
514278
Abstract:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of nitrogen heterocyclic derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
Graham S. Poindexter - Old Saybrook CT Marc Bruce - Wallingford CT Graham Johnson - Madison CT Michael Kozlowski - Palo Alto CA Karen LeBoulluec - Wallingford CT Ivo Monkovic - Durham CT Ramakrishna Seethala - Cranbury NJ Charles P. Sloan - Wallingford CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31435 A61K 3155 C07D40112 C07D41314
US Classification:
514218
Abstract:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperazine and homopiperazine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
Graham S. Poindexter - Old Saybrook CT Marc Bruce - Wallingford CT Graham Johnson - Madison CT Karen LeBoulluec - Wallingford CT Charles P. Sloan - Wallingford CT
Assignee:
Bristol-Myers Squibb Company - New York NY
International Classification:
A61K 31445 C07V21186
US Classification:
514318
Abstract:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperidine and tetrahydropyridine derivatives of 4-phenyl-1,4-dihydropyridines of Formula I. ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
Karen L. Leboulluec - Durham CT Katherine S. Takaki - Middletown CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 3116 C07C23305
US Classification:
514630
Abstract:
There is provided novel spirocyclopropyl fluorene derivatives having the general Formula I ##STR1## wherein R, R. sup. 1 and X are as defined herein which are useful as melatonergic agents.
Mohegan Sun
Fitness Center Representative
Mohegan Sun Mar 2018 - Mar 2019
Entertainment and Sports
Middlesex Community College, Ct Sep 2014 - Dec 2014
Adjunct Faculty
Middlesex Community College, Ct Oct 2010 - Apr 2013
Yoga and Sound Therapy Instructor
Manchester Community College Oct 2010 - Apr 2013
Adjunct Faculty
Education:
Quinnipiac University 2003 - 2005
Master of Science, Masters, Communications
Middlesex Community College
Peabody Veterans Memorial High School
University of Massachusetts Lowell
Bachelors, Bachelor of Science, Chemistry
University of Vermont
Doctorates, Doctor of Philosophy, Organic Chemistry
Skills:
Social Media Editing Public Speaking Blogging Research Entrepreneurship Marketing Online Marketing Advertising Nonprofits Marketing Strategy Training Copywriting Integrated Marketing Web Design Photoshop Strategic Planning Graphic Design Adobe Creative Suite Wellness Wellbeing Indesign Website Development Web Content Photography Illustrator University Teaching Publication Planning Publication Development Publications Production Web Content Management Html Multimedia Marketing Communications Visual Identity Systems Css Visual Storytelling Publication Design Branding and Identity Video Production Publication Production