Karen E Davies

Author:

Karen A. Davies

ISBN #:

0595241832

Author:

Karen A. Davies

ISBN #:

0595748902

Author:

Karen Davies

ISBN #:

0566071630

Author:

Karen Davies

ISBN #:

9129587522

US Patent:

20020040713, Apr 11, 2002

Filed:

Nov 7, 2001

Appl. No.:

10/007617

Inventors:

Robert Eisele - San Diego CA, US
Karen Davies - San Diego CA, US
Nelson Holton - Boulder CO, US
Tim Kline - Boulder CO, US
Ian Smith - Boulder CO, US

Assignee:

Dura Pharmaceuticals, Inc.

International Classification:

B05D007/14
A61M015/00
A61M016/00
B65D083/06

US Classification:

128/203210, 128/203150

Abstract:

A drug powder inhaler has a cover plate pivotably attached to a lid on an inhaler housing. A lever is pivotably attached to the cover plate. A blister pack disk is rotatably mounted on the housing under the cover plate. A powder duct in the housing extends from a staging chamber underneath one end of the lever to an aerosolizing chamber. An actuator in the housing is pressed to shear open a blister on the blister pack disk and thereby deliver the drug dose contents of the blister into the staging chamber. A switch senses pressure in the mouthpiece and switches on a motor spinning an impeller within the aerosolizing chamber, when inhalation is detected.

US Patent:

20020189615, Dec 19, 2002

Filed:

Jun 13, 2001

Appl. No.:

09/882372

Inventors:

Adam Henry - San Diego CA, US
Robert Eisele - Carlsbad CA, US
Thomas Jackson - La Jolla CA, US
Karen Davies - Vista CA, US
Dan Moore - San Diego CA, US

International Classification:

A61M015/00

US Classification:

128/203210

Abstract:

A dry powder inhaler includes systems to prevent or inhibit inadvertent delivery of multiple doses. A latching or locking actuation button prevents closing the inhaler and release of a subsequent dose, until the first dose is inhaled. The actuation button is released, under control of an electronic controller linked to a sensor which senses inhalation. A latching system prevents closing the inhaler until the latching system is released, helping the patient to avoid inadvertently releasing multiple doses. The latching system may include a lockout, also controlled by an electronic controller or microprocessor, which prevents closing the inhaler until the released dose is inhaled. A visual warning system may also be provided to indicate a potential inadvertent multiple dose condition to the patient.

US Patent:

61162388, Sep 12, 2000

Filed:

Dec 2, 1997

Appl. No.:

8/982320

Inventors:

Thomas R. Jackson - San Diego CA
Karen Davies - San Diego CA
Jeff Chen - Palo Alto CA
Mike Ligotke - San Diego CA
Allan Cameron - Westlake Village CA

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61M 1500
A61M 1600
B05D 714
B65D 8306

US Classification:

12820315

Abstract:

A dry powder inhaler has a slider for incrementally advancing a blister disk, to provide successive doses of a dry powder pharmaceutical. A blister disk is rotatably supported on a spindle on a deck plate of the inhaler. A powder port, an advancing slot, and a lifter slot extend through the deck plate. A slider is attached to the deck plate and movable between open and closed positions. As the slider is opened, a litter moves up on a ramp on the slider to shear open a blister, so that the blister contents can be mixed with air and inhaled. As the slider is moved back to the closed position, the lifter is withdrawn and an advancing finger turns the disk to bring the next blister into position for opening to provide the next dose to the patient.

US Patent:

D3954994, Jun 23, 1998

Filed:

Apr 8, 1996

Appl. No.:

D/052913

Inventors:

Robert F. Eisele - San Diego CA
Karen Davies - San Diego CA
Allan Cameron - Santa Monica CA
Greg Halus - Woodland Hills CA
Nelson Holton - Boulder CO
Tim Kline - Boulder CO
Ian Smith - Boulder CO

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

2404

US Classification:

D24110

US Patent:

60067470, Dec 28, 1999

Filed:

Mar 20, 1997

Appl. No.:

8/821753

Inventors:

Robert Eisele - San Diego CA
Karen Davies - San Diego CA
Jeffrey Chen - San Diego CA
Bernard Greenspan - San Diego CA

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61M 1500
A61M 1508

US Classification:

12820315

Abstract:

A dry powder inhaler has a lid pivotally attached to an inhaler housing. A medicine containing cartridge is attached to the top of the housing and includes a cartridge ring with apertures for holding dry powdered medicine. A slide-groove assembly located on the underside of the lid advances the cartridge ring to a next aperture when a user first opens, then closes the lid. A venturi air passageway assembly is contained within the housing of the dry powdered inhaler. The venturi air passageway assembly includes a tapered inlet section, a throat section, and a tapered outlet section. A pressure switch is advantageously located within the housing for actuating the mixing process within the mixing chamber. During inhalation, the pressure switch contained within the housing actuates the motor driven impeller within the mixing chamber of the inhaler when the pressure within the venturi air passageway reaches a predetermined level. The pressure at which the pressure switch closes corresponds to a specifically calibrated inhalation flow rate.

US Patent:

62730851, Aug 14, 2001

Filed:

Jan 5, 1999

Appl. No.:

9/226054

Inventors:

Robert Eisele - San Diego CA
Karen Davies - San Diego CA
Jeffrey Chen - San Diego CA
Bernard Greenspan - San Diego CA

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61M 1500

US Classification:

12820315

Abstract:

A dry powder inhaler has a lid pivotally attached to an inhaler housing. A medicine containing cartridge is attached to the top of the housing and includes a cartridge ring with apertures for holding dry powdered medicine. A slide-groove assembly located on the underside of the lid advances the cartridge ring to a next aperture when a user first opens, then closes the lid. A venturi air passageway assembly is contained within the housing of the dry powdered inhaler. The venturi air passageway assembly includes a tapered inlet section, a throat section, and a tapered outlet section. A pressure switch is advantageously located within the housing for actuating the mixing process within the mixing chamber. During inhalation, the pressure switch contained within the housing actuates the motor driven impeller within the mixing chamber of the inhaler when the pressure within the venturi air passageway reaches a predetermined level. The pressure at which the pressure switch closes corresponds to a specifically calibrated inhalation flow rate.

US Patent:

59212373, Jul 13, 1999

Filed:

Jul 22, 1996

Appl. No.:

8/681103

Inventors:

Robert F. Eisele - San Diego CA
Karen Davies - San Diego CA
Nelson Holton - Boulder CO
Tim Kline - Boulder CO
Ian Smith - Boulder CO

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61M 1500

US Classification:

12820321

Abstract:

A drug powder inhaler has a cover plate pivotably attached to a lid on an inhaler housing. A lever is pivotably attached to the cover plate. A blister pack disk is rotatably mounted on the housing under the cover plate. A powder duct in the housing extends from a staging chamber underneath one end of the lever to an aerosolizing chamber. An actuator in the housing is pressed to shear open a blister on the blister pack disk and thereby deliver the drug dose contents of the blister into the staging chamber. A switch senses pressure in the mouthpiece and switches on a motor spinning an impeller within the aerosolizing chamber, when inhalation is detected.

US Patent:

D453613, Feb 9, 1999

Filed:

Dec 2, 1997

Appl. No.:

D/080183

Inventors:

Allan Cameron - Westlake Village CA
Thomas R. Jackson - San Diego CA
Karen Davies - San Diego CA

Assignee:

Dura Pharmaceuticals, Inc. - San Diego CA

International Classification:

0903

US Classification:

D 9341