Justin Xu Zhao

US Patent:

58665455, Feb 2, 1999

Filed:

Jan 11, 1996

Appl. No.:

8/578613

Inventors:

William K. Hagmann - Westfield NJ
Justin J. Zhao - Jersey City NJ
Malcolm MacCoss - Freehold NJ
Adnan M. Mjalli - San Diego CA

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 3800
C07K 500

US Classification:

514 18

Abstract:

This invention relates to substituted ketone derivatives of formula (I) useful in the treatment of inflammation in lung, central nervous system, kidney, joints, endocardium, pericardium, eyes, ears, skin, gastrointestinal tract and urogenital system. More particularly, this invention relates to substituted ketone drivatives that are useful inhibitors of interleukin-1. beta. converting enzyme (ICE). Interleukin-1. beta. converting enzyme (ICE) has been identified as the enzyme responsible for converting precursor interleukin-1. beta. (IL-1. beta. ) to biologically active IL-1. beta.

US Patent:

20180357548, Dec 13, 2018

Filed:

Apr 30, 2015

Appl. No.:

14/701275

Inventors:

- Mountain View CA, US
Yading Song - London, GB
Justin Zhao - New York NY, US

International Classification:

G06N 5/04
H04L 29/06

Abstract:

A content server stores video and audio, and other media containing songs. One or more seed songs associated with seed lyrics and a client device are obtained. A seed feature vector characterizing the seed lyrics is obtained. A song lyric corpus including candidate feature vectors characterizing candidate song lyrics of candidate songs is accessed. Song lyric features are stored in the song lyric corpus to facilitate identification of candidate lyrics most similar to the seed lyrics. The candidate feature vectors in the song lyric corpus may be reduced-dimension versions of high-dimensional feature vectors quantifying characteristics of the song lyrics. One of the candidate songs is selected according to a measure of similarity between the seed feature vector and one of the candidate feature vectors corresponding to the selected candidate song. A song recommendation including the selected candidate song is generated and provided to the client device associated with the song.