Justin S. Baba - Knoxville TN, US Brian S. Letzen - Coral Springs FL, US
Assignee:
UT-Battelle, LLC - Oak Ridge TN
International Classification:
G01N 21/47 G01B 9/02
US Classification:
356446, 356451
Abstract:
An optical sample is mounted on a spatial-acquisition apparatus that is placed in or on an enclosure. An incident beam is irradiated on a surface of the sample and the specular reflection is allowed to escape from the enclosure through an opening. The spatial-acquisition apparatus is provided with a light-occluding slider that moves in front of the sample to block portions of diffuse scattering from the sample. As the light-occluding slider moves across the front of the sample, diffuse light scattered into the area of the backside of the light-occluding slider is absorbed by back side surface of the light-occluding slider. By measuring a baseline diffuse reflectance without a light-occluding slider and subtracting measured diffuse reflectance with a light-occluding slider therefrom, diffuse reflectance for the area blocked by the light-occluding slider can be calculated.
Charles L. Britton - Alcoa TN, US Brian R. D'Urso - Clinton TN, US Edward Chaum - Memphis TN, US John T. Simpson - Clinton TN, US Justin S. Baba - Knoxville TN, US M. Nance Ericson - Knoxville TN, US Robert J. Warmack - Knoxville TN, US
Assignee:
UT-Battelle, LLC - Oak Ridge TN University of Tennessee Research Foundation - Knoxville TN
International Classification:
A61F 2/16
US Classification:
623 612
Abstract:
In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.
Microfabricated Instruments And Methods To Treat Recurrent Corneal Erosion
Charles L. Britton - Alcoa TN, US Brian R. D'Urso - Clinton TN, US Edward Chaum - Memphis TN, US John T. Simpson - Clinton TN, US Justin S. Baba - Knoxville TN, US M. Nance Ericson - Knoxville TN, US Robert J. Warmack - Knoxville TN, US
Assignee:
UT-Battelle, LLC - Oak Ridge TN University of Tennessee Research Foundation - Knoxville TN
International Classification:
A61M 5/158
US Classification:
604272
Abstract:
In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye.
Method And Apparatus For Non-Invasive Glucose Sensing Through The Eye
Gerard Cote - College Station TX, US Justin Baba - College Station TX, US
International Classification:
A61B005/00
US Classification:
600/318000
Abstract:
There are many inventions described and illustrated herein. In one aspect, the present invention is a system and technique for non-invasively measuring, monitoring, inspecting, characterizing, determining and/or evaluating the blood glucose level in the aqueous humor of the eye of a patient (for example, a diabetic). In one embodiment, the present invention employs a plurality of wavelengths of light (for example, more than three) to measure, monitor, characterize, determine and/or evaluate the blood glucose level or concentration of a patient. The plurality of wavelengths of light may be directed into the aqueous humor of the eye and the reflected light (i.e., the light reflected by the eye) is detected and analyzed to provide information which is representative of the blood glucose level or concentration of the patient.
Method And Apparatus For Orthopedic Implant Assessment
Milton Ericson - Knoxville TN, US Charles Britton - Alcoa TN, US Justin Baba - Knoxville TN, US Robert Warmack - Knoxville TN, US
International Classification:
A61F 2/30 G01M 19/00 G01H 11/00
US Classification:
073649000, 073172000, 623914000
Abstract:
Methods and apparatus are described for orthopedic implant assessment. A method includes characterizing wear of an orthopedic implant including measuring a dimension in a direction that defines a path that passes through an articulating surface of a wear element of the orthopedic implant using at least one thickness sensor. An apparatus includes an orthopedic implant including a wear element having an articulating surface; and at least one thickness sensor coupled to the wear element, the at least one thickness sensor measuring a dimension in a direction that defines a path that passes through the articulating surface of the wear element. A method includes characterizing forces within an orthopedic implant including using a plurality of individually addressable pressure sensors including measuring parasitic impedance between at least two of the plurality of individually addressable pressure sensors.
System And Method For Tracking Motion For Generating Motion Corrected Tomographic Images
James S. Goddard - Knoxville TN, US Justin S. Baba - Knoxville TN, US
Assignee:
UT-Battelle, LLC - Oak Ridge TN
International Classification:
A61B 5/055
US Classification:
382131, 600410
Abstract:
A method and related system for generating motion corrected tomographic images includes the steps of illuminating a region of interest (ROI) to be imaged being part of an unrestrained live subject and having at least three spaced apart optical markers thereon. At least one camera is used to obtain images of the markers. Motion data comprising 3D position and orientation of the markers relative to an initial reference position is then calculated. The at least three spaced apart optical markers and the at least one camera are sufficient in quantity and position to avoid multiple epipolar solutions. Motion corrected tomographic data obtained from the ROI using the motion data is then obtained, where motion corrected tomographic images obtained therefrom.
Timothy E. McKnight - Greenback TN, US Anthony Johnson - Houston TX, US Milton Nance Ericson - Knoxville TN, US Justin S. Baba - Knoxville TN, US John B. Wilgen - Oak Ridge TN, US Boyd Mccutchen Evans, III - Oak Ridge TN, US
Assignee:
UT-BATTELLE, LLC - Oak Ridge TN BAYLOR COLLEGE OF MEDICINE - Houston TX
International Classification:
A61F 2/04 A61F 2/48
US Classification:
623 2368, 623 24
Abstract:
Valve implant systems positionable within a flow passage, the systems having an inlet, an outlet, and a remotely activatable valve between the inlet and outlet, with the valves being operable to provide intermittent occlusion of the flow path. A remote field is applied to provide thermal or magnetic activation of the valves.
Intrinsic Feature-Based Pose Measurement For Imaging Motion Compensation
Systems and methods for generating motion corrected tomographic images are provided. A method includes obtaining first images of a region of interest (ROI) to be imaged and associated with a first time, where the first images are associated with different positions and orientations with respect to the ROI. The method also includes defining an active region in the each of the first images and selecting intrinsic features in each of the first images based on the active region. Second, identifying a portion of the intrinsic features temporally and spatially matching intrinsic features in corresponding ones of second images of the ROI associated with a second time prior to the first time and computing three-dimensional (3D) coordinates for the portion of the intrinsic features. Finally, the method includes computing a relative pose for the first images based on the 3D coordinates.
Vanderbilt University
Research Associate Professor
Institute of Biomedical Engineering University of Tenneessee
Associate Professor
Oak Ridge National Laboratory
R and D Staff-Biomedical R and D Engineer
Texas A&M University 1999 - 2003
Researcher Optical Biosensing Laboratory
Education:
Texas A&M University 1998 - 2003
Doctorates, Doctor of Philosophy, Medical Engineering, Philosophy