Judith J Wurtman

US Patent:

6579899, Jun 17, 2003

Filed:

Jan 27, 2000

Appl. No.:

09/492110

Inventors:

Judith J. Wurtman - Boston MA
Richard J. Wurtman - Boston MA

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

A61K 31405

US Classification:

514419, 514383, 51425215, 514275, 514221, 514649

Abstract:

A method of treating stress in a patient showing stress related symptoms is disclosed, where the method comprises administering to the patient an effective amount of a serotoninergic drug or prodrug. Specific examples of such drugs are described, and include, among others, tryptophan or 5-hydroxytryptophan, or their salts.

US Patent:

RE38566, Aug 17, 2004

Filed:

Sep 4, 1998

Appl. No.:

09/153724

Inventors:

Judith J. Wurtman - Boston MA
Jeff L. Shear - St. Louis MO
Alvin Kershman - St. Louis MO

Assignee:

Walden Laboratories, Inc. - New York NY

International Classification:

A61K 3170

US Classification:

514 54, 514 58, 514 59, 514 60, 514899

Abstract:

A composition is disclosed for alleviating or managing symptoms associated with premenstrual syndrome âPMSâ comprising an effective amount of an aqueous mixture of water and a rapidly digestible carbohydrate blend. The aqueous mixture is essentially free of protein and is characterized by a certain pH and ratio of water to carbohydrate blend. Methods of use of the composition for alleviating or managing symptoms associated with PMS are also disclosed.

US Patent:

7011857, Mar 14, 2006

Filed:

Mar 13, 2002

Appl. No.:

10/096108

Inventors:

Judith J. Wurtman - Boston MA, US
Richard J. Wurtman - Boston MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

A23L 1/0522
A23L 1/09

US Classification:

426 72, 426 73, 426 74, 426804, 426808, 426810

Abstract:

Compositions and methods of losing weight are described that are suitable for individuals susceptible to gastric hyperacidity or gastroesophageal reflux. The compositions include in part a snack food having two or more rapidly digestible carbohydrates, in which the foodstuff or an aqueous mixture of the foodstuff and water has a pH equal to or greater than about 6, and in which the snack is substantially protein-free. The method of weight loss suitable for an individual with gastric hyperacidity includes substantially limiting the individual's caloric intake to about 1400 calories or less for women and 1800 calories or less for men in which the caloric intake includes one or more substantially protein-free snack foodstuffs having two or more rapidly digestible carbohydrates, in which an aqueous mixture of the foodstuff with water has a pH equal to or greater than about 6 and in which the individual loses weight.

US Patent:

43094457, Jan 5, 1982

Filed:

Jun 16, 1980

Appl. No.:

6/159549

Inventors:

Richard J. Wurtman - Boston MA
Judith J. Wurtman - Boston MA

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

A61K 3113

US Classification:

424325

Abstract:

Compositions containing controlled amounts of d-fenfluramine are administered to block the intermittent carbohydrate cravings without necessarily suppressing other food intakes.

US Patent:

46491619, Mar 10, 1987

Filed:

Jun 16, 1986

Appl. No.:

6/874609

Inventors:

Richard J. Wurtman - Boston MA
Judith J. Wurtman - Boston MA
Dermot O'Rourke - Charlestown MA

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

A61K 31135

US Classification:

514654

Abstract:

D-fenfluramine is administered to a human patient having seasonal depression or other forms of bipolar depression in order to alleviate or cure the depression.

US Patent:

54321620, Jul 11, 1995

Filed:

Jan 27, 1994

Appl. No.:

8/187263

Inventors:

Richard J. Wurtman - Boston MA
Judith J. Wurtman - Boston MA

Assignee:

Interneuron Pharmaceuticals, Inc. - Lexington MA

International Classification:

A61K 3170
A61K 3700
A61K 4700
A23J 308

US Classification:

514 23

Abstract:

Methods of reducing post-prandial fluctuations in plasma levels of large, neutral amino acids (LNAA), as well as compositions useful in that method. The foods and compositions comprise a carbohydrate to protein ratio of from about 3:1 to about 8:1 and, in a specific embodiment, a ratio of 7:1, which results in minimizing the variability in responses individuals exhibit to drugs which are LNAA.

US Patent:

56985258, Dec 16, 1997

Filed:

Jun 6, 1995

Appl. No.:

8/471036

Inventors:

Richard J. Wurtman - Boston MA
Judith J. Wurtman - Boston MA

Assignee:

Interneuron Pharmaceuticals, Inc. - Lexington MA

International Classification:

A61K 3170

US Classification:

514 23

Abstract:

Methods of reducing post-prandial fluctuations in plasma levels of large, neutral amino acids (LNAA), as well as compositions useful in that method. The compositions comprise a carbohydrate to protein ratio of from about 3:1 to about 10:1 and, in a specific embodiment, a ratio of 7:1, which results in minimizing the variability in responses which individuals exhibit to drugs which are LNAA.

US Patent:

57600147, Jun 2, 1998

Filed:

Oct 17, 1996

Appl. No.:

8/733308

Inventors:

Judith J. Wurtman - Boston MA
Jeff L. Shear - St. Louis MO
Alvin Kershman - St. Louis MO

Assignee:

Internutria, Inc. - Framingham MA

International Classification:

A61K 3170

US Classification:

514 54

Abstract:

A method of managing or alleviating carbohydrate craving, binge eating, anxiety, or depression entails administering an aqueous carbohydrate blend containing dextrose, dextrin, maltodextrin or a mixture thereof, and starch, pregelatinized starch, or a mixture thereof. The aquous mixture is essentially free of protein, has a pH of less than 6 and has a ratio of water to carbohydrate blend of about 3-12 mL water to 1 g of carbohydrate blend.

Author:

Judith J. Wurtman

ISBN #:

0395354242

Author:

Judith J. Wurtman

ISBN #:

0449911314

Author:

Judith J. Wurtman

ISBN #:

0449910016

Author:

Judith J. Wurtman

ISBN #:

0881671428

Author:

Judith J. Wurtman

ISBN #:

0881676284

Author:

Judith J. Wurtman

ISBN #:

0890042802

Author:

Judith J. Wurtman

ISBN #:

0892563052

Author:

Judith J. Wurtman

ISBN #:

0897663934