Joseph E Dougherty

Author:

Joseph Dougherty

ISBN #:

0595396895

Author:

Joseph Dougherty

ISBN #:

0822203081

US Patent:

20090163406, Jun 25, 2009

Filed:

Sep 30, 2005

Appl. No.:

11/576444

Inventors:

Harley I. Kornblum - Los Angeles CA, US
Daniel H. Geschwind - Santa Monica CA, US
Ichiro Nakano - Los Angeles CA, US
Joseph D. Dougherty - New York NY, US
Jorge Lazareff - Los Angeles CA, US
Paul S. Mischel - Los Angeles CA, US
Michael D. Masterman Smith - Playa Del Rey CA, US
Jing Huan - Los Angeles CA, US
Houman D. Hemmati - Baltimore MD, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 31/70
A61K 31/7088
A61K 38/02
A61K 38/16
A61K 31/20
C40B 40/08
G01N 33/53
A61P 35/00

US Classification:

514 12, 514 44, 514 2, 514 23, 514558, 506 17, 435 721

Abstract:

In one aspect, the invention provides composition and methods for the diagnosis, prognosis and treatment of tumors and cancers, e.g., brain cancers. In one aspect, the invention provides compositions and methods for inhibiting the growth, proliferation, differentiation and/or survival of a neural stem cell or a cancer cell, or progenitor stem cell thereof. In one aspect, the invention provides compositions and methods for identifying the genetic profile of a brain cancer cell or a self-renewing neural cancer stem cell. In one aspect, the invention provides methods employing these profiles to identify compounds that inhibit tumor growth.

US Patent:

6169049, Jan 2, 2001

Filed:

Apr 28, 1997

Appl. No.:

8/847613

Inventors:

John P. Witham - Fountain Valley CA
Clive A. Randall - State College PA
Umesh Kumar - Surfside Beach SC
Joseph P. Dougherty - State College PA

International Classification:

C04B 35468

US Classification:

501137

Abstract:

Hydrothermal BaTiO. sub. 3 crystallites were coated with Bismuth solutions prepared from Bismuth metal-organics and anhydrous solvents. The Bismuth metal-organics were Bi 2-ethylhexanoate and Bi-neodecanoate. Bismuth oxide was also used as a comparison to the Bismuth solutions. BaTiO. sub. 3 ceramics with either 3. 0 wt % equivalent Bismuth oxide or 5. 0 wt % equivalent Bismuth oxide were made by sintering the compacts between 700. degree. C. and 1000. degree. C. BaTiO. sub. 3 ceramics that were coated by Bi-neodecanoate densified >90% theoretical as low as 800. degree. C. for 3. 0 wt % equivalent Bi. sub. 2 O. sub. 3. Average grain sizes of 0. 2-0. 4. mu. m were observed for Bi-coated BaTiO. sub. 3 ceramics, for sintering temperatures below 950. degree. C. Dielectric K versus temperature measurements of Bismuth-coated BaTiO. sub.