Josef Parvizi

US Patent:

20130324878, Dec 5, 2013

Filed:

May 30, 2013

Appl. No.:

13/905377

Inventors:

Josef Parvizi - Palo Alto CA, US

International Classification:

A61B 5/00
A61B 5/04
A61B 5/0476

US Classification:

600544

Abstract:

A digital processor system having one or more processors and memory obtains a time-domain signal representing brain activity, the time-domain signal having a time varying signal value. The system concurrently generates a set of acoustic parameters, including a plurality of time-varying acoustic parameters, where one or more of the plurality of time-varying acoustic parameters is modulated in accordance with at least the signal value of the time-domain signal. The system combines the concurrently generated set of acoustic parameters to produce a representation of an acoustic signal corresponding to the time-domain signal, where the acoustic signal, in audible form, manifests one or more audibly discernible variations across a plurality of stages of a brain activity event.

US Patent:

20210267539, Sep 2, 2021

Filed:

Oct 28, 2020

Appl. No.:

17/083078

Inventors:

- Mountain View CA, US
Chris CHAFE - Woodside CA, US
Josef PARVIZI - Palo Alto CA, US
Jianchun YI - San Jose CA, US
Raymond WOO - Los Altos CA, US
Xingjuan CHAO - Palo Alto CA, US

International Classification:

A61B 5/00
G10L 25/51
H04R 3/04
A61B 5/318
A61B 5/369
A61B 5/389
A61B 5/398

Abstract:

Systems and methods for sonifying electrical signals obtained from a living subject, particularly EEG signals, are disclosed. A time-domain signal representing the activity of an organ is obtained. A voltage of the time-domain signal over a time block is determined. An acoustic signal based on the time-domain signal over the time block is produced. The acoustic signal comprises one or more audibly discernible variations representative of the activity of the organ. If the determined voltage is over a threshold voltage, the time-domain signal is squelched over at least a portion of the time-block as the acoustic signal is produced. The time-domain signal can be squelched by ramping down the signal as an input to produce the acoustic signal. The frequency spectrum of the acoustic signal can also be adjusted as it is produced, such as by flattening the signal and/or attenuating high frequencies along the frequency spectrum of the signal.

US Patent:

20210085235, Mar 25, 2021

Filed:

Jul 8, 2020

Appl. No.:

16/923689

Inventors:

- Mountain View CA, US
Suganya Karunakaran - Sunnyvale CA, US
Alexander M. Grant - Redwood City CA, US
Jianchun Yi - San Jose CA, US
Raymond Woo - Los Altos CA, US
Josef Parvizi - Palo Alto CA, US
Xingjuan Chao - Palo Alto CA, US

International Classification:

A61B 5/00
A61B 5/0476
G06F 9/54
G06N 20/00

Abstract:

The present disclosure provides systems and methods for seizure detection. The method for seizure detection may include receiving a plurality of electroencephalography (EEG) signals over a plurality of channels for a subject, preprocessing the plurality of EEG signals by segmenting the plurality of EEG signals for each channel into a plurality of temporal data segments, extracting a plurality of features from each temporal data segment for each channel, and applying a machine learning algorithm to the plurality of features to perform a seizure binary classification for each temporal data segment for each channel. A control policy may be employed to determine a seizure burden on the aggregated seizure binary classifications. When the seizure burden is equal to or exceeds a threshold, a notification may be generated. The notification may be usable by a healthcare practitioner to assess whether the subject may be at risk of having a seizure.

US Patent:

20200305786, Oct 1, 2020

Filed:

Mar 27, 2019

Appl. No.:

16/367040

Inventors:

- Mountain View CA, US
Chris CHAFE - Woodside CA, US
Josef PARVIZI - Palo Alto CA, US
Jianchun YI - San Jose CA, US
Raymond WOO - Los Altos CA, US
Xingjuan CHAO - Palo Alto CA, US

International Classification:

A61B 5/00
A61B 5/0402
A61B 5/0476
A61B 5/0488
A61B 5/0496
H04R 3/04
G10L 25/51

Abstract:

Systems and methods for sonifying electrical signals obtained from a living subject, particularly EEG signals, are disclosed. A time-domain signal representing the activity of an organ is obtained. A voltage of the time-domain signal over a time block is determined. An acoustic signal based on the time-domain signal over the time block is produced. The acoustic signal comprises one or more audibly discernible variations representative of the activity of the organ. If the determined voltage is over a threshold voltage, the time-domain signal is squelched over at least a portion of the time-block as the acoustic signal is produced. The time-domain signal can be squelched by ramping down the signal as an input to produce the acoustic signal. The frequency spectrum of the acoustic signal can also be adjusted as it is produced, such as by flattening the signal and/or attenuating high frequencies along the frequency spectrum of the signal.

US Patent:

20190343462, Nov 14, 2019

Filed:

Mar 25, 2019

Appl. No.:

16/363159

Inventors:

- Mountain View CA, US
Jianchun YI - San Jose CA, US
Bradley G. BACHELDER - Menlo Park CA, US
Raymond WOO - Los Altos CA, US
Josef PARVIZI - Palo Alto CA, US
Xingjuan CHAO - Palo Alto CA, US

International Classification:

A61B 5/00
A61B 5/0476
A61N 1/36
A61N 1/37
A61B 5/04
A61B 5/042
A61N 1/02

Abstract:

Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.

US Patent:

20150150520, Jun 4, 2015

Filed:

Dec 1, 2014

Appl. No.:

14/557240

Inventors:

- Palo Alto CA, US
Josef Parvizi - Palo Alto CA, US

International Classification:

A61B 5/00
A61B 5/0476
A61B 5/046
A61B 5/0205
A61B 5/0464

Abstract:

A digital processor system obtains at least one time-domain signal representing brain activity and at least one time-domain signal representing heart activity, each having a time-varying signal value. The system produces representations of a plurality of acoustic signals, each of which corresponds to a respective time-domain signal and is produced by concurrently generating a plurality of acoustic parameters, including a plurality of time-varying acoustic parameters. One or more of the plurality of time-varying acoustic parameters is modulated in accordance with at least the signal value of the respective time-domain signal. Each representation of an acoustic signal of the plurality of acoustic signals is further produced by combining the concurrently generated plurality of acoustic parameters to produce the representation of the acoustic signal corresponding to the respective time-domain signal. The system combines the representations of each of the plurality of acoustic signals to produce a combined acoustic signal.