Jonathan E Emeigh

US Patent:

6689804, Feb 10, 2004

Filed:

Jul 16, 2002

Appl. No.:

10/195973

Inventors:

Jiang-Ping Wu - Danbury CT
Terence Alfred Kelly - Ridgefield CT
Rene Lemieux - Plantsville CT
Daniel R. Goldberg - Redding CT
Jonathan Emilian Emeigh - Danbury CT
Ronald John Sorcek - Bethel CT

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A61K 314188

US Classification:

514387, 514386, 544242, 544333, 5483031, 5483027

Abstract:

A method for treating inflammatory and immune cell-mediated diseases by the administration of compounds of the formula I Exemplary are:.

US Patent:

6964956, Nov 15, 2005

Filed:

Jun 3, 2003

Appl. No.:

10/453175

Inventors:

Charles L. Cywin - Bethel CT, US
Zhidong Chen - New Milford CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ming-Hong Hao - Ridgefield CT, US
Eugene Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Daniel Richard Marshall - Norwalk CT, US
Peter Nemoto - Southbury CT, US
Ronald John Sorcek - Bethel CT, US
Sanxing Sun - Danbury CT, US
Jiang-Ping Wu - Danbury CT, US
Tina Morwick - New Milford CT, US
Jonathan Emeigh - Gilbertsville PA, US

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A61K031/4365
A61K031/551
A61K031/496
C07D495/04

US Classification:

51421115, 51421704, 514218, 5142282, 51425304, 514301, 540492, 540544, 540575, 540597, 544 60, 544362, 546114

Abstract:

Disclosed are compounds of formula (I): wherein Rand Rare defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

US Patent:

6974870, Dec 13, 2005

Filed:

Dec 6, 2003

Appl. No.:

10/730172

Inventors:

Charles L. Cywin - Bethel CT, US
Can Mao - New Milford CT, US
Jonathan Emeigh - Danbury CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ming-Hong Hao - Ridgefield CT, US
Eugene Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Daniel Richard Marshall - Norwalk CT, US
Tina Morwick - New Milford CT, US
Peter Nemoto - Southbury CT, US
Ronald John Sorcek - Bethel CT, US
Sanxing Sun - Danbury CT, US
Jiang-Ping Wu - Danbury CT, US
Erick Young - Danbury CT, US
Darren DiSalvo - New Milford CT, US
John Ginn - New Milford CT, US
Pier Cirillo - Woodbury CT, US

Assignee:

Boehringer Ingelheim Phamaceuticals, Inc. - Ridgefield CT

International Classification:

C07D495/04
A61K031/4365
A61K031/497
A61K031/5377

US Classification:

546114, 514218, 51421115, 51421704, 5142338, 51425304, 51425505, 514256, 5142282, 514301, 540492, 540544, 540575, 540597, 544 582, 544 60, 544127, 544 33, 544362, 544405

Abstract:

Disclosed are compounds of formula (I): wherein Rand Rare defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

US Patent:

7405225, Jul 29, 2008

Filed:

Aug 18, 2005

Appl. No.:

11/206707

Inventors:

Charles L. Cywin - Bethel CT, US
Zhidong Chen - New Milford CT, US
Jonathan Emeigh - Danbury CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ming-Hong Hao - Ridgefield CT, US
Eugene Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Daniel Richard Marshall - Norwalk CT, US
Tina Morwick - New Milford CT, US
Peter Nemoto - Southbury CT, US
Ronald John Sorcek - Bethel CT, US
Sanxing Sun - Danbury CT, US
Jiang-Ping Wu - Danbury CT, US

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A01N 43/42
A61K 31/44
C07D 471/02
C07D 491/02
C07D 498/02
C07D 513/02
C07D 515/02

US Classification:

514301, 546114

Abstract:

Disclosed are compounds of formula (I):.

US Patent:

7550494, Jun 23, 2009

Filed:

Sep 25, 2003

Appl. No.:

10/672412

Inventors:

Jiang-Ping Wu - Danbury CT, US
Terence Alfred Kelly - Ridgefield CT, US
Rene M. Lemieux - Plantsville CT, US
Daniel R. Goldberg - Redding CT, US
Jonathan Emillian Emeigh - Danbury CT, US
Ronald John Sorcek - Bethel CT, US

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A61K 31/418
C07D 403/00
D07D 239/00

US Classification:

514387, 544242, 544333, 5483031, 5483027, 514386

Abstract:

Compounds of the formula I.

US Patent:

6492408, Dec 10, 2002

Filed:

Jun 27, 2000

Appl. No.:

09/604312

Inventors:

Jiang-Ping Wu - Danbury CT
Terence Alfred Kelly - Ridgefield CT
Rene Lemieux - Plantsville CT
Daniel R. Goldberg - New Canaan CT
Jonathan Emilian Emeigh - Danbury CT
Ronald John Sorcek - Bethel CT

Assignee:

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

International Classification:

A61K 314188

US Classification:

514387, 514386, 544242, 544333, 5483031, 5483027

Abstract:

Compounds of the formula I which are useful for treating or preventing inflammatory and immune cell-mediated diseases. Exemplary are:.