Dr. Silver graduated from the Duke University School of Medicine in 1986. He works in Asheville, NC and specializes in Surgery , Neurological. Dr. Silver is affiliated with Mission Hospital.
Peter Lu - Palo Alto CA, US Michael Belmares - San Jose CA, US Johannes Schweizer - Mountain View CA, US Jon Silver - San Jose CA, US
Assignee:
Arbor Vita Corporation - Sunnyvale CA
International Classification:
C12Q 1/70
US Classification:
435005000
Abstract:
The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.
Peter S. Lu - Palo Alto CA, US Michael P. Belmares - San Jose CA, US Johannes Schweizer - Mountain View CA, US Jon Silver - San Jose CA, US
Assignee:
Arbor Vista Corporation - Sunnyvale CA
International Classification:
C12Q 1/70
US Classification:
435 5
Abstract:
The invention provides methods for detecting influenza B from its NS1 protein. The NS1 protein is present in detectable levels in clinical samples and can be detected using antibodies that are panspecific for influenza B without binding to influenza A or other viruses.
The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.