John C Hedenstrom

US Patent:

20080207675, Aug 28, 2008

Filed:

Feb 3, 2006

Appl. No.:

11/815491

Inventors:

David Q. Ma - Saint Paul MN, US
Christopher S. Perman - Saint Paul MN, US
Raymond D. Skwierczynski - Cambridge MA, US
John C. Hedenstrom - Saint Paul MN, US

International Classification:

A61K 31/437
C07D 471/12
A61P 1/04

US Classification:

514293, 546 82

Abstract:

Pharmaceutical formulations in an aqueous gel formulation including 1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine are provided. Methods of use and kits are also provided.

US Patent:

20090163532, Jun 25, 2009

Filed:

Feb 3, 2006

Appl. No.:

11/883665

Inventors:

Christopher S. Perman - Saint Paul MN, US
Raymond D. Skwierczynski - Saint Paul MN, US
David Q. Ma - Saint Paul MN, US
John C. Hedenstrom - Saint Paul MN, US

Assignee:

Coley Pharmaceutical Group, Inc. - New York NY

International Classification:

A61K 31/437
A61K 31/4738
A61P 31/00

US Classification:

514293, 514303

Abstract:

Aqueous gel formulations, including an immune response modifier (IRM), such as those chosen from imidazoquinoline amines, tetrahydroimidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, imidazonaphthyridine amines, imidazotetrahydronaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines, oxazolopyridine amines, thiazolopyridine amines, oxazolonaphthyridine amines, thiazolonaphthyridine amines, pyrazolopyridine amines, pyrazoloquinoline amines, tetrahydropyrazoloquinoline amines, pyrazolonaphthyridine amines, tetrahydropyrazolonaphthyridine amines, and 1H-imidazo dimers fused to pyridine amines, quinoline amines, tetrahydroquinoline amines, naphthyridine amines, or tetrahydronaphthyridine amines, are provided. Methods of use and kits are also provided.

US Patent:

20160101173, Apr 14, 2016

Filed:

Dec 16, 2015

Appl. No.:

14/971230

Inventors:

- SAINT PAUL MN, US
CHRISTOPHER S. PERMAN - BROOKLYN PARK MN, US
RAYMOND D. SKWIERCZYNSKI - ANDOVER MA, US
JOHN C. HEDENSTROM - SAINT PAUL MN, US

International Classification:

A61K 39/39
A61M 31/00
A61K 47/20
A61K 47/10
A61K 31/4745
A61K 9/06

Abstract:

Aqueous gel formulations, including an immune response modifier (IRM), such as those chosen from imidazoquinoline amines, tetrahydroimidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, imidazonaphthyridine amines, imidazotetrahydronaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines, oxazolopyridine amines, thiazolopyridine amines, oxazolonaphthyridine amines, thiazolonaphthyridine amines, pyrazolopyridine amines, pyrazoloquinoline amines, tetrahydropyrazoloquinoline amines, pyrazolonaphthyridine amines, tetrahydropyrazolonaphthyridine amines, and 1H-imidazo dimers fused to pyridine amines, quinoline amines, tetrahydroquinoline amines, naphthyridine amines, or tetrahydronaphthyridine amines, are provided. Methods of use and kits are also provided.