John W Gore

Author:

John Gore

ISBN #:

0836969383

Author:

John Gore

ISBN #:

0850670187

Author:

John C. Gore

ISBN #:

0080327850

Author:

John C. Gore

ISBN #:

0815145101

US Patent:

7777488, Aug 17, 2010

Filed:

Jul 14, 2008

Appl. No.:

12/172706

Inventors:

John C. Gore - Nashville TN, US
Qin Qin - Baltimore MD, US
Robin A. De Graaf - Hamden CT, US

Assignee:

Vanderbilt University - Nashville TN

International Classification:

G01V 3/00

US Classification:

324309, 324307

Abstract:

In another aspect, the present invention relates to a method for NMR measurements of an arbitrarily shaped region of interest of a living subject. In one embodiment, the method comprises the steps of applying a broad bandwidth of RF pulses to the arbitrarily shaped region of interest to obtain a corresponding spectrum, wherein substantially entire range of chemical shifts in the spectrum is excited from the arbitrarily shaped region of interest, interleaving a plurality of radial k-lines in radial k-space per excitation with non-selective refocusing pulses and obtaining spatial localization for the spectrum of the arbitrarily shaped region of interest.

US Patent:

8168804, May 1, 2012

Filed:

Jun 30, 2008

Appl. No.:

12/165369

Inventors:

Wellington Pham - Brentwood TN, US
John C Gore - Nashville TN, US

Assignee:

Vanderbilt University - Nashville TN

International Classification:

C07D 403/06
A61K 31/404

US Classification:

548455, 514414

Abstract:

A compound of the following formula:.

US Patent:

20120164635, Jun 28, 2012

Filed:

Mar 6, 2012

Appl. No.:

13/413241

Inventors:

Wellington Pham - Brentwood TN, US
John C. Gore - Nashville TN, US

International Classification:

G01N 21/64
G01N 21/17
C07D 403/08
C07D 403/14
C07K 17/02

US Classification:

435 61, 548455, 530300, 530408, 5303913, 435 29

Abstract:

A compound of the following formula:wherein Ris SOH; Ris chosen from carboxylic acid group and SOH; and Ris chosen from Cl, carboxylic acid group, amino, amino-carboxylic acid group, amido group, amino-amido group, and methods of use related to imaging.

US Patent:

20170299676, Oct 19, 2017

Filed:

Apr 18, 2017

Appl. No.:

15/490597

Inventors:

- Nashville TN, US
John GORE - Nashville TN, US

International Classification:

G01R 33/44
G01R 33/36

Abstract:

Methods for operating a magnetic resonance apparatus and systems therefrom are provided. A method includes generating, via a coil former surrounding a subject or object of interest and disposed in the magnetic resonance apparatus, a plurality of field modes external to the subject or object, measuring for each of the plurality of external field modes, an associated internal field produced within the subject or object, generating, via the coil former a combination of external modes to produce a target internal field in the subject or object, and measuring nuclear magnetic resonance signals due to the resulting field from the combination to acquire an image or spectrum of the subject or object.

US Patent:

20160125224, May 5, 2016

Filed:

Nov 4, 2015

Appl. No.:

14/932386

Inventors:

- Nashville TN, US
John C. Gore - Nashville TN, US

International Classification:

G06K 9/00
G06T 7/60

Abstract:

In the various embodiments, cell size imaging is performed using a method that relies upon the acquisition of gradient echo and spin echo data during contrast agent (CA) passage through tissue and estimation of “perturber” size using the ratio of ΔR* and ΔR. When measured at CA equilibrium, the magnetic field perturbations, and associated MRI signal changes, are determined by the cellular features and not the vasculature. Thus, in cell size imaging the cells act as the perturbers.

US Patent:

20140134107, May 15, 2014

Filed:

Nov 7, 2013

Appl. No.:

14/074099

Inventors:

- Nashville TN, US
Donald D. Nolting - Nashville TN, US
John C. Gore - Nashville TN, US

International Classification:

A61K 51/04
C07D 277/28

US Classification:

424 189, 435 25, 548204

Abstract:

Embodiments of the present disclosure provide for a compound, methods of making a compound, a probe, methods of making a probe, pharmaceutical compositions including a probe or a compound, methods of using a probe, methods of imaging, diagnosing, localizing, monitoring, and/or assessing a disease (e.g., cancer, diseases caused by inflammation (e.g., arthritis, cardiovascular disease, and the like)), and the like, and/or related biological events using a probe, kit for imaging, diagnosing, localizing, monitoring, and/or assessing a disease, and/or related biological events, using a probe, and the like.