John W Benbow

Author:

John Benbow

ISBN #:

0198563388

US Patent:

7485641, Feb 3, 2009

Filed:

Jun 18, 2007

Appl. No.:

11/764445

Inventors:

David W. Piotrowski - Waterford CT, US
Yu Hui - Groton CT, US
John W. Benbow - Norwich CT, US

Assignee:

Pfizer, Inc. - New York NY

International Classification:

C07D 401/14
C07D 403/14
C07D 405/14
C07D 407/14
C07D 409/14
A61K 31/4025
A61K 31/404
A61K 31/445
A61K 31/506
A61K 31/53
A61P 3/10

US Classification:

514245, 514248, 514256, 5142662, 514335, 514415, 514424, 514426, 544209, 544237, 544283, 544326, 546208, 548469, 548518

Abstract:

The invention provides compounds of formula (1),.

US Patent:

7671072, Mar 2, 2010

Filed:

Nov 15, 2004

Appl. No.:

10/580615

Inventors:

John W. Benbow - Norwich CT, US
Daniel W. Kung - Salem CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/4155
A61K 31/435
C07D 401/02
C07D 231/10

US Classification:

514341, 514406, 5462754, 5483714, 5483731

Abstract:

The present invention provides compounds of formula (I) the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs, wherein R, R, and Rare as defined herein; pharmaceutical compositions thereof; combinations thereof; and uses thereof in the treatment of, inter alia, conditions, diseases, and symptoms including, inter alia, Alzheimer's Disease, cancer, dementia, depression, diabetes, hair loss, schizophrenia, and stroke.

US Patent:

7709473, May 4, 2010

Filed:

Sep 27, 2004

Appl. No.:

10/575395

Inventors:

John William Benbow - Norwich CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/54
A61K 31/535
A61K 31/497
A61K 31/505
C07D 417/00
C07D 413/00
C07D 403/00
C07D 239/02

US Classification:

5142278, 544 60, 544122, 544295, 544329, 544330, 5142355, 51425214, 514275

Abstract:

The invention relates to compounds of formula (I) prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R, R, Rand Rare as defined herein; pharmaceutical compositions thereof; and uses thereof.

US Patent:

7977367, Jul 12, 2011

Filed:

Sep 9, 2009

Appl. No.:

12/556086

Inventors:

John William Benbow - Norwich CT, US
Jihong Lou - San Diego CA, US
Jeffrey Allen Pfefferkorn - Mystic CT, US
Meihua Mike Tu - Mystic CT, US

Assignee:

Pfizer Inc - New York NY

International Classification:

A61K 31/415

US Classification:

514399, 544405, 546309, 548255, 5483415, 5483761, 549356

Abstract:

The present invention provides Formula (1A) compounds.

US Patent:

8071606, Dec 6, 2011

Filed:

Jan 20, 2010

Appl. No.:

12/690186

Inventors:

John William Benbow - Norwich CT, US
Jeffrey Allen Pfefferkorn - Mystic CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/4965

US Classification:

51425506, 544406, 5462681, 549356

Abstract:

The present invention provides compounds of Formula (I).

US Patent:

8329920, Dec 11, 2012

Filed:

May 26, 2011

Appl. No.:

13/116398

Inventors:

John William Benbow - Norwich CT, US
Jihong Lou - San Diego CA, US
Jeffrey Allen Pfefferkorn - Mystic CT, US
Meihua Mike Tu - Mystic CT, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 233/00

US Classification:

5483351, 544405, 546114, 5462727, 548255, 5483731, 549356, 549429

Abstract:

The present invention provides Formula (1A) compounds.

US Patent:

20040192698, Sep 30, 2004

Filed:

Mar 22, 2004

Appl. No.:

10/805885

Inventors:

John Benbow - Norwich CT, US
Margaret Chu-Moyer - Old Lyme CT, US
Daniel Kung - Salem CT, US

Assignee:

Pfizer Inc.

International Classification:

A61K031/498
C07D487/04

US Classification:

514/250000, 544/346000

Abstract:

The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R, R, R, and Rare as defined herein; pharmaceutical compositions thereof; and uses thereof.

US Patent:

20110130365, Jun 2, 2011

Filed:

Jul 15, 2009

Appl. No.:

13/055952

Inventors:

John W. Benbow - Norwich CT, US
Jihong Lou - San Diego CA, US
Jeffrey A. Pferfferkorn - Mystic CT, US
Meihua M. Tu - Mystic CT, US

International Classification:

A61K 31/675
C07D 401/12
A61K 31/497
A61K 31/444
A61K 31/4439
A61K 31/506
A61K 31/4709
C07D 403/12
C07F 9/6558
A61P 3/10

US Classification:

514 85, 544405, 51425505, 546261, 514335, 5462754, 514341, 544331, 514275, 5462721, 514340, 546159, 514313, 544295, 544337

Abstract:

The present invention provides Formula (1A) XN O R 3 HN R 5 O R 4 R 2 R 1 (1A) 5 compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the glucokinase enzyme, where X, R 1, R 2, R 3, R 4, and R 5 are as described herein.