Julie Magarian Blander - North Haven CT, US Johan Garaude - New York NY, US
Assignee:
MOUNT SINAI SCHOOL OF MEDICINE - New York NY
International Classification:
A61K 39/00
US Classification:
4241921, 435325
Abstract:
Provided are methods for inducing an anti-tumor immune response by immunizing a mammal with a composition comprising a tumor cell which expresses a NLR ligand and/or TLR ligand-TAA fusion protein or with an activated DC which has internalized a tumor cell which expresses an NLR- and/or TLR ligand-TAA fusion protein.
Methods And Compositions For Cancer Immunotherapy Using Flagellin-Tumor Associated Antigen Fusion Protein Expressing Tumor Cells
Provided are methods for inducing an anti-tumor immune response by immunizing a mammal with a composition comprising a tumor cell which expresses a NLR ligand and/or TLR ligand-TAA fusion protein or with an activated DC which has internalized a tumor cell which expresses an NLR- and/or TLR ligand-TAA fusion protein.