Jirong Lu

age ~57

from Carmel, IN

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Also known as:

Jirong Wang
Lu Lu Jirong

Phone and address:: 13793 Stone Dr, Carmel, IN 46032

Connected to:

Jirong Lu Phones & Addresses

13793 Stone Dr, Carmel, IN 46032
6232 Vancouver Ct, Indianapolis, IN 46236
Greenfield, IN
27 Topton Way, Saint Louis, MO 63105
Hamilton, IN

Work

Company:

Eli lilly and company
Oct 2016
Position:

Distinguished research fellow

Education

Degree:

Doctorates, Doctor of Philosophy
School / High School:

University of Oregon
1987 to 1992
Specialities:

Biochemistry

Skills

Protein Chemistry • Drug Discovery • Biotechnology • Antibodies • Drug Development • Monoclonal Antibodies • Biochemistry • Oncology • Clinical Development • Protein Purification • Life Sciences • Pharmacology • Biomarkers • Pharmaceutical Industry • In Vitro • Purification • Lifesciences • Cro • Assay Development • Adme • Drug Metabolism • Pharmacokinetics • Target Identification • Hplc

Industries

Pharmaceuticals

Us Patents

Humanized Anti-Il-1Β Antibodies
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US Patent:

7541033, Jun 2, 2009
Filed:

Jan 21, 2004
Appl. No.:

10/542508
Inventors:

Craig Duane Dickinson - San Diego CA, US
Alain Philippe Vasserot - Carlsbad CA, US
Jeffry Dean Watkins - Encinitas CA, US
Jirong Lu - Indianapolis IN, US
Assignee:

Applied Molecular Evolution, Inc. - San Diego CA
International Classification:

C07K 16/00
C07K 16/24
C12P 21/08
A61K 39/395
A61K 39/00
US Classification:

4241451, 5303871, 5303873, 53038815, 5303882, 53038823, 4241301, 4241331, 4241371
Abstract:

The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind mature human IL-1 Beta. These antibodies, or antigen-binding portions thereof, generally exhibit high binding affinities (low kff values), reduced deamidation compared to the native antibody, and can be used to treat various diseases such as rheumatoid arthritis, osteoarthritis, or neuroinflammation.

Fsh And Fsh Variant Formulations, Products And Methods
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US Patent:

7563763, Jul 21, 2009
Filed:

Aug 26, 2005
Appl. No.:

11/212423
Inventors:

James Arthur Hoffmann - Greenwood IN, US
Jirong Lu - Indianapolis IN, US
Assignee:

Ares Trading S.A. - Aubonne
International Classification:

A61K 38/24
A61K 31/14
A61K 31/05
US Classification:

514 2, 530399, 530398
Abstract:

This invention relates to FSH or a FSH variant containing an alpha and beta subunit contained in formulations, and articles of manufacture. The invention provides advantageous new proteins and nucleic acids, multi-use pharmaceutical solutions, formulations and products of said proteins and nucleic acids where none approved for commercial use had previously existed having such extended use indications. These products are particularly useful in therapeutic regimens for increasing serum levels of FSH or a FSH variant over a period of treatment. Thus, inter alia, the invention fills the need for convenient products of FSH or from a FSH variant.

Humanized Anti-Il-1 Beta Antibodies
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US Patent:

7714120, May 11, 2010
Filed:

Apr 23, 2009
Appl. No.:

12/428558
Inventors:

Craig Duane Dickinson - San Diego CA, US
Alain Philippe Vasserot - Carlsbad CA, US
Jeffry Dean Watkins - Encinitas CA, US
Jirong Lu - Indianapolis IN, US
Assignee:

Applied Molecule Evolution, Inc. - San Diego CA
International Classification:

C07H 21/04
C12P 21/06
C12N 15/74
US Classification:

536 2353, 536 231, 536 235, 4353201, 435328, 435 691, 435 696
Abstract:

The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind mature human IL-1 Beta. These antibodies, or antigen-binding portions thereof, generally exhibit high binding affinities (low kff values), reduced deamidation compared to the native antibody, and can be used to treat various diseases such as rheumatoid arthritis, osteoarthritis, or neuroinflammation.

Anti-Il-17 Antibodies
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US Patent:

7838638, Nov 23, 2010
Filed:

Dec 5, 2006
Appl. No.:

12/095398
Inventors:

Barrett Allan - Encinitas CA, US
Chi-Kin Chow - Brownsburg IN, US
Ling Liu - Carmel IN, US
Jirong Lu - Carmel IN, US
Jonathan Wendell Tetreault - Indianapolis IN, US
Assignee:

Eli Lilly and Company - Indianapolis IN
International Classification:

C07K 16/24
US Classification:

5303873, 53038823
Abstract:

Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.

Pegylated Aβ Fab
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US Patent:

8066999, Nov 29, 2011
Filed:

Jan 9, 2008
Appl. No.:

12/521309
Inventors:

Ronald Bradley DeMattos - Zionsville IN, US
Jirong Lu - Carmel IN, US
Assignee:

Eli Lilly and Company - Indianapolis IN
International Classification:

A61K 39/395
A61K 39/44
C07K 16/18
US Classification:

4241391, 4241331, 4241781, 5303871, 5303879, 5303911, 530866
Abstract:

A method to treat conditions associated with Aβ peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human Aβ peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.

Anti-Il-17 Antibodies
view source
US Patent:

8110191, Feb 7, 2012
Filed:

Oct 21, 2010
Appl. No.:

12/908892
Inventors:

Barrett Allan - Encinitas CA, US
Chi-Kin Chow - Brownsburg IN, US
Ling Liu - Carmel IN, US
Jirong Lu - Carmel IN, US
Jonathan Wendell Tetreault - Indianapolis IN, US
Ying Tang - San Diego CA, US
Assignee:

Eli Lilly and Company - Indianapolis IN
International Classification:

A61K 39/395
C07K 16/24
US Classification:

4241451, 4241331, 4241581, 5303873, 53038823
Abstract:

Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.

C-Met Antibodies
view source
US Patent:

8217148, Jul 10, 2012
Filed:

Nov 18, 2009
Appl. No.:

12/620617
Inventors:

Julian Davies - La Jolla CA, US
Ling Liu - Carmel IN, US
Jirong Lu - Carmel IN, US
Peter Edward Vaillancourt - Del Mar CA, US
Mark Andrew Wortinger - Greenwood IN, US
Wei Zeng - Carmel IN, US
Assignee:

Eli Lilly and Company - Indianapolis IN
International Classification:

C07K 16/00
US Classification:

5303871, 5303888
Abstract:

Provided are monoclonal antibodies, antigen-binding fragments thereof, and combinations of the foregoing, that bind to, and inhibit the activity of, c-Met, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c-Met.

C-Met Antibodies
view source
US Patent:

8398974, Mar 19, 2013
Filed:

Jun 25, 2012
Appl. No.:

13/531858
Inventors:

Julian Davies - La Jolla CA, US
Ling Liu - Carmel IN, US
Jirong Lu - Carmel IN, US
Peter Edward Vaillancourt - Del Mar CA, US
Mark Andrew Wortinger - Greenwood IN, US
Wei Zeng - Carmel IN, US
Assignee:

Eli Lilly and Company - Indianapolis IN
International Classification:

A61K 39/395
US Classification:

4241301, 4241411, 4241431, 4241551
Abstract:

Provided are monoclonal antibodies, antigen-binding fragments thereof, and combinations of the foregoing, that bind to, and inhibit the activity of, c-Met, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by c-Met.

Resumes

Distinguished Research Fellow

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Location:

13793 Stone Dr, Carmel, IN 46032

Industry:

Pharmaceuticals

Work:

Eli Lilly and Company
Distinguished Research Fellow
Eli Lilly and Company Oct 2009 - Oct 2012
Senior Research Advisor
Eli Lilly and Company Oct 2009 - Oct 2012
Senior Research Fellow
Eli Lilly and Company Sep 2005 - Oct 2009
Research Advisor
Eli Lilly and Company Jan 2000 - Jan 2005
Principle Research Scientist

Education:

University of Oregon 1987 - 1992
Doctorates, Doctor of Philosophy, Biochemistry Sichuan University 1982 - 1986
Bachelors, Bachelor of Science, Chemistry

Skills:

Protein Chemistry
Drug Discovery
Biotechnology
Antibodies
Drug Development
Monoclonal Antibodies
Biochemistry
Oncology
Clinical Development
Protein Purification
Life Sciences
Pharmacology
Biomarkers
Pharmaceutical Industry
In Vitro
Purification
Lifesciences
Cro
Assay Development
Adme
Drug Metabolism
Pharmacokinetics
Target Identification
Hplc

Other Social Networks

Jirg Lu

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